Literature DB >> 27015420

Construction of Substituted Benzenes via Pd-Catalyzed Cross-Coupling/Cyclization Reaction of Vinyl Halides and Terminal Alkynes.

Meihua Xie1, Shengke Wang1, Jun Wang1, Kuang Fang1, Changqing Liu1, Chao Zha1, Jing Jia1.   

Abstract

A tandem Sonogashira coupling/cyclization/aromatization sequence of β-halo vinyl sulfones/ketones with terminal alkynes has been developed for the construction of benzene rings. Polysubstituted functionalized benzenes containing a sulfonyl or an acyl group could be obtained in up to 95% yield.

Entities:  

Year:  2016        PMID： 27015420     DOI： 10.1021/acs.joc.6b00308

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  2 in total

1.  Metal-Free Synthesis of Functionalized Tetrasubstituted Alkenes by Three-Component Reaction of Alkynes, Iodine, and Sodium Sulfinates.

Authors:  Jitan Zhang; Zhenda Liang; Jun Wang; Ziyi Guo; Changqing Liu; Meihua Xie
Journal:  ACS Omega       Date:  2018-12-21

Review 2.  Synthesis of polysubstituted arenes through organocatalytic benzannulation.

Authors:  Qian Zhao; Cheng Peng; Gu Zhan; Bo Han
Journal:  RSC Adv       Date:  2020-11-10       Impact factor: 4.036
  2 in total

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