Alexander W Levis1, Daphna Harel2, Linda Kwakkenbos3, Marie-Eve Carrier4, Luc Mouthon5, Serge Poiraudeau6, Susan J Bartlett7, Dinesh Khanna8, Vanessa L Malcarne9, Maureen Sauve10, Cornelia H M van den Ende11, Janet L Poole12, Anne A Schouffoer13, Joep Welling14, Brett D Thombs1. 1. Lady Davis Institute for Medical Research, Jewish General Hospital, and McGill University, Montreal, Quebec, Canada. 2. New York University, New York. daphna.harel@nyu.edu. 3. Lady Davis Institute for Medical Research, Jewish General Hospital, and McGill University, Montreal, Quebec, Canada, and Radboud University, Nijmegen, The Netherlands. 4. Lady Davis Institute for Medical Research, Jewish General Hospital. 5. Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, and Hôpital Cochin, Paris, France. 6. Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, and IFR Handicap INSERM, Paris, France. 7. McGill University, Montreal, Quebec, Canada. 8. University of Michigan Scleroderma Program, Ann Arbor. 9. San Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California. 10. Scleroderma Society of Ontario, Hamilton, and Scleroderma Society of Canada, Ottawa, Ontario, Canada. 11. Sint Maartenskliniek, Nijmegen, The Netherlands. 12. University of New Mexico, Albuquerque. 13. Leiden University Medical Center, Leiden, The Netherlands. 14. NVLE Dutch patient organization for systemic autoimmune diseases, Utrecht, The Netherlands.
Abstract
OBJECTIVE: To develop and validate a short form of the Cochin Hand Function Scale (CHFS), which measures hand disability, for use in systemic sclerosis, using objective criteria and reproducible techniques. METHODS: Responses on the 18-item CHFS were obtained from English-speaking patients enrolled in the Scleroderma Patient-Centered Intervention Network Cohort. CHFS unidimensionality was verified using confirmatory factor analysis, and an item response theory model was fit to CHFS items. Optimal test assembly (OTA) methods identified a maximally precise short form for each possible form length between 1 and 17 items. The final short form selected was the form with the least number of items that maintained statistically equivalent convergent validity, compared to the full-length CHFS, with the Health Assessment Questionnaire (HAQ) disability index (DI) and the physical function domain of the 29-item Patient-Reported Outcomes Measurement Information System (PROMIS-29). RESULTS: There were 601 patients included. A 6-item short form of the CHFS (CHFS-6) was selected. The CHFS-6 had a Cronbach's alpha of 0.93. Correlations of the CHFS-6 summed score with HAQ DI (r = 0.79) and PROMIS-29 physical function (r = -0.54) were statistically equivalent to the CHFS (r = 0.81 and r = -0.56). The correlation with the full CHFS was high (r = 0.98). CONCLUSION: The OTA procedure generated a valid short form of the CHFS with minimal loss of information compared to the full-length form. The OTA method used was based on objective, prespecified criteria, but should be further studied for viability as a general procedure for shortening patient-reported outcome measures in health research.
OBJECTIVE: To develop and validate a short form of the Cochin Hand Function Scale (CHFS), which measures hand disability, for use in systemic sclerosis, using objective criteria and reproducible techniques. METHODS: Responses on the 18-item CHFS were obtained from English-speaking patients enrolled in the SclerodermaPatient-Centered Intervention Network Cohort. CHFS unidimensionality was verified using confirmatory factor analysis, and an item response theory model was fit to CHFS items. Optimal test assembly (OTA) methods identified a maximally precise short form for each possible form length between 1 and 17 items. The final short form selected was the form with the least number of items that maintained statistically equivalent convergent validity, compared to the full-length CHFS, with the Health Assessment Questionnaire (HAQ) disability index (DI) and the physical function domain of the 29-item Patient-Reported Outcomes Measurement Information System (PROMIS-29). RESULTS: There were 601 patients included. A 6-item short form of the CHFS (CHFS-6) was selected. The CHFS-6 had a Cronbach's alpha of 0.93. Correlations of the CHFS-6 summed score with HAQ DI (r = 0.79) and PROMIS-29 physical function (r = -0.54) were statistically equivalent to the CHFS (r = 0.81 and r = -0.56). The correlation with the full CHFS was high (r = 0.98). CONCLUSION: The OTA procedure generated a valid short form of the CHFS with minimal loss of information compared to the full-length form. The OTA method used was based on objective, prespecified criteria, but should be further studied for viability as a general procedure for shortening patient-reported outcome measures in health research.
Authors: Miyabi Ishihara; Daphna Harel; Brooke Levis; Alexander W Levis; Kira E Riehm; Nazanin Saadat; Marleine Azar; Danielle B Rice; Tatiana A Sanchez; Matthew J Chiovitti; Pim Cuijpers; Simon Gilbody; John P A Ioannidis; Lorie A Kloda; Dean McMillan; Scott B Patten; Ian Shrier; Bruce Arroll; Charles H Bombardier; Peter Butterworth; Gregory Carter; Kerrie Clover; Yeates Conwell; Felicity Goodyear-Smith; Catherine G Greeno; John Hambridge; Patricia A Harrison; Marie Hudson; Nathalie Jetté; Kim M Kiely; Anthony McGuire; Brian W Pence; Alasdair G Rooney; Abbey Sidebottom; Adam Simning; Alyna Turner; Jennifer White; Mary A Whooley; Kirsty Winkley; Andrea Benedetti; Brett D Thombs Journal: Depress Anxiety Date: 2018-09-20 Impact factor: 8.128
Authors: Erin L Merz; Linda Kwakkenbos; Marie-Eve Carrier; Shadi Gholizadeh; Sarah D Mills; Rina S Fox; Lisa R Jewett; Heidi Williamson; Diana Harcourt; Shervin Assassi; Daniel E Furst; Karen Gottesman; Maureen D Mayes; Tim P Moss; Brett D Thombs; Vanessa L Malcarne Journal: BMJ Open Date: 2018-03-06 Impact factor: 2.692
Authors: Daphna Harel; Sarah D Mills; Linda Kwakkenbos; Marie-Eve Carrier; Karen Nielsen; Alexandra Portales; Susan J Bartlett; Vanessa L Malcarne; Brett D Thombs Journal: BMJ Open Date: 2019-02-22 Impact factor: 2.692
Authors: Rayanne C Ferreira; Thiago S Torres; Maria Das Graças B Ceccato; Daniel Rb Bezerra; Brett D Thombs; Paula M Luz; Daphna Harel Journal: JMIR Public Health Surveill Date: 2022-03-29