Dataset of STAT5A status in breast cancer.

We analysed STAT5A gene expression in breast cancer using the Oncomine database. We exemplify four representative studies showing that STAT5A is generally downregulated in breast cancer.

Specifications Table

Value of the data

We show that in different independent studies STAT5A is downregulated in breast cancer.

The downregulation of STAT5A supports a tumour suppressor role for STAT5A in breast cancer and is consistent with our recent discovery that STAT5A is a p53-target gene [2].

High levels of STAT5A indicate a good prognosis in breast cancer and it assessment can be used in the clinics as part of a multigene prognostic test (Fig. 1).

Fig. 1

Downregulation of STAT5A expression in breast cancer (from Oncomine).

Data

We show that STAT5A is downregulated in breast cancer using several large-scale gene expression analyses available at Oncomine: https://www.oncomine.org/resource/main.html [1].

Experimental design, materials and methods

We used the publicly available Oncomine search to find the status of STAT5A in breast cancer.

Subject area	Biology
More specific subject area	Cancer
Type of data	Figure
How data was acquired	Database Oncomine[1]
Data format	Filtered and analyzed
Experimental factors	Not applicable
Experimental features	We query Oncomine for STAT5A and breast cancer
Data source location	Montréal, Québec
Data accessibility	Data is within this article.