Literature DB >> 27014642

Clinicopathological Overview of Granulomatous Prostatitis: An Appraisal.

Rajeshwari Kumbar1, Nandkumar Dravid2, Dhiraj Nikumbh3, Ashish Patil2, Karibasappa Gundabaktha Nagappa4.   

Abstract

INTRODUCTION: Granulomatous prostatitis is a rare inflammatory condition of the prostate. Granulomatous prostatitis is important because, it mimics prostatic carcinoma clinically and hence the diagnosis can be made only by histopathological examination. AIM: To study the histomorphological features and to know the prevalence of granulomatous prostatitis.
MATERIALS AND METHODS: Histopathological records of 1,203 prostatic specimens received in the Department of the Pathology over a period of five years (June 2009 - June 2014). Seventeen cases of histopathologically, diagnosed granulomatous prostatitis were retrieved and reterospective data was collected from the patient's records.
RESULTS: Out of 17 cases of granulomatous prostatitis, we encountered 9 cases of non-specific granulomatous prostatitis, 5 cases of xanthogranulomatous prostatitis and 3 cases of specific tubercular prostatitis. The common age ranged from 51-75 years (mean 63 years) with mean PSA level of 15.8ng/ml. Six patients showed focal hypoechoic areas on TRUS and 11 cases revealed hard and fixed nodule on DRE.
CONCLUSION: Non-specific granulomatous prostatitis is the most common type of granulomatous prostatitis. There is no specific pattern of clinical, biochemical and ultrasound findings that allows the diagnosis of granulomatous prostatitis or differentiates it from prostatic carcinoma. Hence, histomorphological diagnosis is the gold standard in differentiating various prostatic lesions.

Entities:  

Keywords:  Histomorphology; Non-specific infection; Prostate; Specific infection

Year:  2016        PMID: 27014642      PMCID: PMC4740601          DOI: 10.7860/JCDR/2016/15365.7146

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  12 in total

1.  Elevated prostate specific antigen serum levels after intravesical instillation of bacillus Calmette-Guerin.

Authors:  D Leibovici; A Zisman; Z Chen-Levyi; H Cypele; Y I Siegel; S Faitelovich; A Lindner
Journal:  J Urol       Date:  2000-11       Impact factor: 7.450

2.  Nonspecific (idiopathic) granulomatous prostatitis associated with low-grade prostatic adenocarcinoma.

Authors:  J Fernando Val-Bernal; Laura Zaldumbide; M Francisca Garijo; M Carmen González-Vela
Journal:  Ann Diagn Pathol       Date:  2004-08       Impact factor: 2.090

3.  Elevation of prostate specific antigen from bacillus Calmette-Guerin-induced granulomatous prostatitis.

Authors:  R R Bahnson
Journal:  J Urol       Date:  1991-11       Impact factor: 7.450

4.  Granulomatous prostatitis: a clinicopathological study.

Authors:  R L Bryan; J Newman; A Campbell; G Fitzgerald; C Kadow; J M O'Brien
Journal:  Histopathology       Date:  1991-11       Impact factor: 5.087

5.  Granulomatous prostatitis: a reminder to clinicians.

Authors:  K Shanggar; M Z Zulkifli; A H Razack; N Dublin
Journal:  Med J Malaysia       Date:  2010-03

6.  Granulomatous prostatitis on needle biopsy.

Authors:  J R Oppenheimer; H Kahane; J I Epstein
Journal:  Arch Pathol Lab Med       Date:  1997-07       Impact factor: 5.534

7.  Granulomatous prostatitis--an infrequent diagnosis.

Authors:  Harsh Mohan; Amanjit Bal; Raj Pal Singh Punia; Amarpreet Singh Bawa
Journal:  Int J Urol       Date:  2005-05       Impact factor: 3.369

8.  The clinical spectrum of granulomatous prostatitis: a report of 200 cases.

Authors:  T J Stillwell; D E Engen; G M Farrow
Journal:  J Urol       Date:  1987-08       Impact factor: 7.450

9.  Granulomatous prostatitis linked to HLA-DRB1*1501.

Authors:  Richard B Alexander; Dean L Mann; Andrew A Borkowski; Marcelo Fernandez-Vina; Elena N Klyushnenkova; James Kodak; Kathleen J Propert; Marcie Kincaid
Journal:  J Urol       Date:  2004-06       Impact factor: 7.450

10.  prostatic xanthoma: a mimic of prostatic adenocarcinoma.

Authors:  T J Sebo; D G Bostwick; G M Farrow; J N Eble
Journal:  Hum Pathol       Date:  1994-04       Impact factor: 3.466

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  4 in total

1.  Granulomatous prostatitis: clinical and histomorphologic survey of the disease in a tertiary care hospital.

Authors:  Prakriti Shukla; Hanni V Gulwani; Sukhpreet Kaur
Journal:  Prostate Int       Date:  2017-01-12

2.  Prostatic Abscess on Xanthogranulomatous Prostatitis: Uncommon Complication of an Uncommon Disease.

Authors:  Youness Jabbour; Hamza Lamchahab; Sumba Harrison; Hafsa El Ouazzani; Tarik Karmouni; Khalid El Khader; Abdellatif Koutani; Ahmed Iben Attya Andaloussi
Journal:  Case Rep Urol       Date:  2018-08-29

3.  Granulomatous prostatitis mimicking prostate cancer in a patient with psoriatic arthritis: a case report.

Authors:  Luigi De Luca; Felice Crocetto; Biagio Barone; Massimiliano Creta; Salvatore Pesce; Achille Aveta; Maria Raffaela Campanino; Ciro Imbimbo; Nicola Longo
Journal:  Future Sci OA       Date:  2020-06-17

Review 4.  Differential diagnosis of uncommon prostate diseases: combining mpMRI and clinical information.

Authors:  Chao Han; Lina Zhu; Xiang Liu; Shuai Ma; Yi Liu; Xiaoying Wang
Journal:  Insights Imaging       Date:  2021-06-16
  4 in total

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