| Literature DB >> 27012389 |
Michael Karsy1, Jian Guan1, Adam Cohen2, Howard Colman3, Randy L Jensen4.
Abstract
Meningiomas are benign tumors of the central nervous system, with low recurrence risk for World Health Organization (WHO) grade I lesions but a high risk for WHO grade II and III lesions. Current standard treatments include maximum safe surgical resection when indicated and radiation. Only three systemic therapies alpha-interferon, somatostatin receptor agonists, and vascular endothelial growth factor inhibitors are currently recommended by the National Comprehensive Cancer Network for treatment of recurrent meningioma. This paper aims to review medical approaches in the treatment of meningiomas.Entities:
Keywords: Genetics; Medical management; Meningiomas; Targeted treatment
Mesh:
Substances:
Year: 2016 PMID: 27012389 DOI: 10.1016/j.nec.2015.11.002
Source DB: PubMed Journal: Neurosurg Clin N Am ISSN: 1042-3680 Impact factor: 2.509