Cerebral hemi-atrophy and seizures: Some facts.

Sir,

We read an interesting case series by Jaiswal et al.[1] The authors have found that congenital hemi-atrophy had better seizure control than that in patients with HHE syndrome, that is, acquired cerebral hemi-atrophy. We also conducted a study on such patients.[2] Of course the theme of the study was different but still we would like to mention some salient similarities and differences as under:

Cerebral hemispheric and cerebellar atrophy was present in 28.1% of the patients in our series, whereas it was present in 40.5% of the total patients in this series.

Hippocampal sclerosis was present in 16% of patients in our series, whereas it was present in 38% of the patients in the present series.

Phenytoin adverse effects were significantly associated with HHE syndrome.

These differences are of importance once we compare the data from various regions, as there are wide demographic differences in various parts of India and as are the level of medical facilities and awareness. So the aim of this correspondence is to make aware the differing clinical, radiological and pharmacological patterns in our country.