Literature DB >> 27011551

Predictive Factors for Surgical Intervention in Patients over the Age of 80 with Adhensive Small-Bowel Obstruction.

Zheng Lou1, Fei-Hu Yan1,2, Shi-Jie Hu3, Rong-Gui Meng1, Wei Zhang1, En-da Yu1, Chuan-Gang Fu1.   

Abstract

Adhensive small-bowel obstruction (SBO) remains a common cause of admission to surgical wards around the world. Given the growing elderly population, the number of elderly patients with adhensive SBO can be expected to increase substantially. Timely and appropriate treatment would improve morbidity and mortality rates in elderly patients with adhensive SBO. However, accurately determining which patients should undergo surgical treatment during the hospitalization remains difficult. The aim of this study was to identify predictive factors for surgical intervention in patients aged over 80 years presenting with SBO due to postoperative adhesions. A clinical and radiological data for the assessment of patients presenting with adhensive SBO were collected. A logistic regression model was applied to identify risk factors that would predict the need of surgical intervention. A total of 21 patients (13 males, 8 females) were treated during a 3.5-year period. The mean age was 85.5 ± 4.7 years, ranging from 80 to 97 years. There is no significant difference in age (group 1 87.6 ± 5.9 years vs. group 2 84.8 ± 4.3 years, p = 0.262) between two groups. Serious coexisting diseases were noted in 13 (61.9 %, 13/21) patients. Primary hypertension, cardiac diseases, and diabetes mellitus were common coexisting conditions. However, there is no significant difference in comorbidities (40 vs. 68.8 %, p = 0.325) between group 1 and group 2. Adhensive SBO was successfully treated with conservative treatment in 16 patients (76.2 %, 16/21, group 2), whereas conservative treatment failed in 5 patients (23.8 %, 5/21, group 1), who subsequently underwent laparotomy. Postoperative complication rate was 14.3 % (wound infection, 1/5) and mortality was 0 % (0/5) in group 1. One patient death was recorded in group 2 (1/16, 6.3 %). The overall mean hospital stay was 10.0 ± 5.9 days (range 3-27 days). Group 1 had a longer hospital stay than group 2. However, the difference did not reach the significant level (12.8 ± 8.2 vs. 9.1 ± 5.9 days, p = 0.274). On univariate analysis, the need for surgical intervention was significantly associated with granulocyte percentage (2.768, 0.961-7.975, p = 0.059), CT findings of free intraabdominal fluid (28.000, 1.988-394.405, p = 0.014), and level of albumin (0.265, 0.073-0.970, p = 0.045). On multivariate analysis, the predictive factor was free intraabdominal fluid (28.000, 1.988-394.405, p = 0.014). Conservative treatment remains a major consideration in patients over the age of 80. Although major cases of adhensive SBO are successfully treated with conservative methods, some fail to respond, and the independent risk factor for surgical indication is free intraabdominal fluid.

Entities:  

Keywords:  Adhesion; Risk factors; Small-bowel obstruction; Surgery; The elderly

Year:  2015        PMID: 27011551      PMCID: PMC4775599          DOI: 10.1007/s12262-015-1275-y

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  14 in total

1.  Effects of different pulmonary surfactants in the prevention of postoperative intraabdominal adhesion formation.

Authors:  Yavuz Yilmaz; Istemi H Celik; Arzu Pampal; Gamze Demirel; Ferda Topal; Serife S Oguz; Sibel S Kilicoglu; Ibrahim O Ozen; Ugur Dilmen
Journal:  J Pediatr Surg       Date:  2012-08       Impact factor: 2.545

2.  Complications and death after surgical treatment of small bowel obstruction: A 35-year institutional experience.

Authors:  B T Fevang; J Fevang; L Stangeland; O Soreide; K Svanes; A Viste
Journal:  Ann Surg       Date:  2000-04       Impact factor: 12.969

3.  Emergency major abdominal surgery in patients over 85 years of age.

Authors:  Ph Zerbib; J F Kulick; G Lebuffe; A Khoury-Helou; I Plenier; J P Chambon
Journal:  World J Surg       Date:  2005-07       Impact factor: 3.352

4.  How conservatively can postoperative small bowel obstruction be treated?

Authors:  D Seror; E Feigin; A Szold; T M Allweis; M Carmon; S Nissan; H R Freund
Journal:  Am J Surg       Date:  1993-01       Impact factor: 2.565

5.  Intra-abdominal administration of bevacizumab diminishes intra-peritoneal adhesions.

Authors:  Dejan Ignjatovic; Kristine Aasland; Marianne Pettersen; Stale Sund; Yin Chen; Milan Spasojevic; Jens Marius Nesgaard
Journal:  Am J Surg       Date:  2010-03-15       Impact factor: 2.565

6.  Etiology of small bowel obstruction.

Authors:  G Miller; J Boman; I Shrier; P H Gordon
Journal:  Am J Surg       Date:  2000-07       Impact factor: 2.565

7.  Multifactorial analysis of prognostic factors in emergency abdominal surgery in patients above 80 years. Analysis of 154 consecutive cases.

Authors:  R Reiss; A A Deutsch; I Nudelman; H Gutman
Journal:  Int Surg       Date:  1989 Apr-Jun

8.  Factors predicting the recurrence of adhesive small-bowel obstruction.

Authors:  H Barkan; S Webster; S Ozeran
Journal:  Am J Surg       Date:  1995-10       Impact factor: 2.565

9.  Long-term outcome after hospitalization for small-bowel obstruction.

Authors:  J Landercasper; T H Cogbill; W H Merry; R T Stolee; P J Strutt
Journal:  Arch Surg       Date:  1993-07

10.  Small bowel obstruction: the role of nonoperative treatment in simple intestinal obstruction and predictive criteria for strangulation obstruction.

Authors:  L S Bizer; R W Liebling; H M Delany; M L Gliedman
Journal:  Surgery       Date:  1981-04       Impact factor: 3.982

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