| Literature DB >> 27010822 |
Khaoula Boukari1, Cécile Caoduro1, Raoudha Kacem1, Nadia Skandrani1, Christophe Borg2, Hatem Boulahdour1, Tijani Gharbi1, Régis Delage-Mourroux3, Eric Hervouet3, Marc Pudlo4, Fabien Picaud5.
Abstract
Carbon nanotubes (CNT) are currently used as a promising family of nanovectors able to deliver different types of therapeutic molecules. Several applications dealing with CNT used as drug nanocarriers have been developed since their ability to penetrate into the cells has been proved. CNT can thus load several active molecules to various cells. In this paper, we will use molecular dynamic simulation to describe theoretically the potential of CNT to transport and deliver DNA through the formation of protamine-DNA-CNT complex.Entities:
Keywords: Nanovectorization; Protamine; Simulation
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Year: 2016 PMID: 27010822 DOI: 10.1007/s00232-016-9890-5
Source DB: PubMed Journal: J Membr Biol ISSN: 0022-2631 Impact factor: 1.843