Literature DB >> 27010822

Nanovectorization of DNA Through Cells Using Protamine Complexation.

Khaoula Boukari1, Cécile Caoduro1, Raoudha Kacem1, Nadia Skandrani1, Christophe Borg2, Hatem Boulahdour1, Tijani Gharbi1, Régis Delage-Mourroux3, Eric Hervouet3, Marc Pudlo4, Fabien Picaud5.   

Abstract

Carbon nanotubes (CNT) are currently used as a promising family of nanovectors able to deliver different types of therapeutic molecules. Several applications dealing with CNT used as drug nanocarriers have been developed since their ability to penetrate into the cells has been proved. CNT can thus load several active molecules to various cells. In this paper, we will use molecular dynamic simulation to describe theoretically the potential of CNT to transport and deliver DNA through the formation of protamine-DNA-CNT complex.

Entities:  

Keywords:  Nanovectorization; Protamine; Simulation

Mesh:

Substances:

Year:  2016        PMID: 27010822     DOI: 10.1007/s00232-016-9890-5

Source DB:  PubMed          Journal:  J Membr Biol        ISSN: 0022-2631            Impact factor:   1.843


  42 in total

Review 1.  Are there molecules of nucleoprotamine?

Authors:  E Raukas; R H Mikelsaar
Journal:  Bioessays       Date:  1999-05       Impact factor: 4.345

2.  Single-walled carbon nanotubes are a new class of ion channel blockers.

Authors:  Ki Ho Park; Manish Chhowalla; Zafar Iqbal; Federico Sesti
Journal:  J Biol Chem       Date:  2003-09-30       Impact factor: 5.157

Review 3.  Applications of carbon nanotubes in drug delivery.

Authors:  Alberto Bianco; Kostas Kostarelos; Maurizio Prato
Journal:  Curr Opin Chem Biol       Date:  2005-10-17       Impact factor: 8.822

4.  Promises, facts and challenges for carbon nanotubes in imaging and therapeutics.

Authors:  K Kostarelos; A Bianco; M Prato
Journal:  Nat Nanotechnol       Date:  2009-09-27       Impact factor: 39.213

5.  Understanding the mechanism of protamine in solid lipid nanoparticle-based lipofection: the importance of the entry pathway.

Authors:  Diego Delgado; Ana del Pozo-Rodríguez; Maria Ángeles Solinís; Alicia Rodríguez-Gascón
Journal:  Eur J Pharm Biopharm       Date:  2011-06-25       Impact factor: 5.571

6.  Protamine sulfate enhances lipid-mediated gene transfer.

Authors:  F L Sorgi; S Bhattacharya; L Huang
Journal:  Gene Ther       Date:  1997-09       Impact factor: 5.250

7.  Insertion kinetics of small nucleotides through single walled carbon nanotube.

Authors:  A Clavier; S Kraszewski; C Ramseyer; F Picaud
Journal:  J Biotechnol       Date:  2012-12-20       Impact factor: 3.307

8.  Experimental and simulation studies of unusual current blockade induced by translocation of small oxidized PEG through a single nanopore.

Authors:  S Cabello-Aguilar; A Abou Chaaya; F Picaud; M Bechelany; C Pochat-Bohatier; S Yesylevskyy; S Kraszewski; M C Bechelany; F Rossignol; E Balanzat; J M Janot; P Miele; P Dejardin; S Balme
Journal:  Phys Chem Chem Phys       Date:  2014-09-07       Impact factor: 3.676

9.  Interactions Between Cultured Neurons and Carbon Nanotubes: A Nanoneuroscience Vignette.

Authors:  Antonietta Sucapane; Giada Cellot; Maurizio Prato; Michele Giugliano; Vladimir Parpura; Laura Ballerini
Journal:  J Nanoneurosci       Date:  2009-06-01

10.  Nanotubes.

Authors:  C N Rao; B C Satishkumar; A Govindaraj; M Nath
Journal:  Chemphyschem       Date:  2001-02-16       Impact factor: 3.102

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