Literature DB >> 27009266

Metabolic control of arthritis: Switch pathways to treat.

George C Tsokos1.   

Abstract

A shunting of glucose metabolism to the pentose phosphate pathway in rheumatoid arthritis T cells causes exhaustion of oxidants, enhanced cell proliferation, and differentiation toward the T helper 1 (TH1) and TH17 programs (Yanget al, this issue).
Copyright © 2016, American Association for the Advancement of Science.

Entities:  

Mesh：

Year:  2016        PMID： 27009266     DOI： 10.1126/scitranslmed.aaf4953

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  10 in total

Review 1.  Immunometabolism in the development of rheumatoid arthritis.

Authors:  Cornelia M Weyand; Jörg J Goronzy
Journal:  Immunol Rev       Date:  2020-01-27       Impact factor: 12.988

2.  Fat T cells go to the joint.

Authors:  George C Tsokos
Journal:  Nat Immunol       Date:  2017-08-22       Impact factor: 25.606

Review 3.  Metabolic signatures of T-cells and macrophages in rheumatoid arthritis.

Authors:  Cornelia M Weyand; Markus Zeisbrich; Jörg J Goronzy
Journal:  Curr Opin Immunol       Date:  2017-05-21       Impact factor: 7.486

Review 4.  Immunometabolism in early and late stages of rheumatoid arthritis.

Authors:  Cornelia M Weyand; Jörg J Goronzy
Journal:  Nat Rev Rheumatol       Date:  2017-03-31       Impact factor: 20.543

5.  Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro.

Authors:  Inkyung Kang; Christian Hundhausen; Stephen P Evanko; Prasanthi Malapati; Gail Workman; Christina K Chan; Cliff Rims; Gary S Firestein; David L Boyle; Kevin M MacDonald; Jane H Buckner; Thomas N Wight
Journal:  Matrix Biol Plus       Date:  2022-04-26

6.  PGK1, a glucose metabolism enzyme, may play an important role in rheumatoid arthritis.

Authors:  Yan Zhao; Xinfeng Yan; Xia Li; Yabing Zheng; Shufeng Li; Xiaotian Chang
Journal:  Inflamm Res       Date:  2016-06-24       Impact factor: 4.575

Review 7.  Immunometabolic Regulation of Interleukin-17-Producing T Helper Cells: Uncoupling New Targets for Autoimmunity.

Authors:  Katrina J Binger; Beatriz F Côrte-Real; Markus Kleinewietfeld
Journal:  Front Immunol       Date:  2017-03-21       Impact factor: 7.561

8.  N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation.

Authors:  Zhenke Wen; Ke Jin; Yi Shen; Zhen Yang; Yinyin Li; Bowen Wu; Lu Tian; Stanford Shoor; Niall E Roche; Jorg J Goronzy; Cornelia M Weyand
Journal:  Nat Immunol       Date:  2019-02-04       Impact factor: 25.606

Review 9.  Metabolic Checkpoints in Rheumatoid Arthritis.

Authors:  Valentina Pucino; Michelangelo Certo; Gilda Varricchi; Giancarlo Marone; Francesco Ursini; Francesca Wanda Rossi; Amato De Paulis; Claudio Mauro; Karim Raza; Christopher Dominic Buckley
Journal:  Front Physiol       Date:  2020-04-17       Impact factor: 4.566

Review 10.  T-Cell Metabolism in Hematopoietic Cell Transplantation.

Authors:  Hung D Nguyen; Sandeepkumar Kuril; David Bastian; Xue-Zhong Yu
Journal:  Front Immunol       Date:  2018-02-09       Impact factor: 7.561
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.