Literature DB >> 27008462

New Insights into IL-10 Dependent and IL-10 Independent Mechanisms of Regulatory B Cell Immune Suppression.

Achilleas Floudas1,2, Sylvie Amu3, Padraic G Fallon4,5.   

Abstract

Regulatory B (Breg) cells are important regulators of immune responses and in recent years our understanding of their phenotypical and functional characteristics has improved considerably. Initially all suppressive capabilities of Breg cells were attributed to the actions of the anti-inflammatory cytokine interleukin (IL)-10 secreted by Breg cells. Recent studies however, highlight additional and novel mechanisms that influence both the expansion of Breg cells and their capacity to suppress immunity. Here we provide an overview of the complexity of Breg cell populations and address the newly discovered IL-10 independent mechanisms of Breg cell expansion and immune-suppression.

Entities:  

Keywords:  B cells; IL-10; inflammation; regulatory B cells

Mesh：

Substances：

Year:  2016        PMID： 27008462     DOI： 10.1007/s10875-016-0263-8

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN： 0271-9142            Impact factor:   8.317


  70 in total

1.  Identifying regulatory B cells (B10 cells) that produce IL-10 in mice.

Authors:  Takashi Matsushita; Thomas F Tedder
Journal:  Methods Mol Biol       Date:  2011

2.  Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice.

Authors:  Qing Ding; Melissa Yeung; Geoffrey Camirand; Qiang Zeng; Hisaya Akiba; Hideo Yagita; Geetha Chalasani; Mohamed H Sayegh; Nader Najafian; David M Rothstein
Journal:  J Clin Invest       Date:  2011-08-08       Impact factor: 14.808

3.  Novel function of B cell-activating factor in the induction of IL-10-producing regulatory B cells.

Authors:  Min Yang; Lingyun Sun; Shengjun Wang; King-Hung Ko; Huaxi Xu; Bo-Jian Zheng; Xuetao Cao; Liwei Lu
Journal:  J Immunol       Date:  2010-03-05       Impact factor: 5.422

4.  Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model.

Authors:  Sylvie Amu; Sean P Saunders; Mitchell Kronenberg; Niamh E Mangan; Ann Atzberger; Padraic G Fallon
Journal:  J Allergy Clin Immunol       Date:  2010-03-20       Impact factor: 10.793

5.  IL-10 producing B cells partially restore E2-mediated protection against EAE in PD-L1 deficient mice.

Authors:  Jun Zhang; Gil Benedek; Sheetal Bodhankar; Andrew Lapato; Arthur A Vandenbark; Halina Offner
Journal:  J Neuroimmunol       Date:  2015-06-11       Impact factor: 3.478

6.  Regeneration of B cell subsets after transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis.

Authors:  Petra Roll; Arumugam Palanichamy; Christian Kneitz; Thomas Dorner; Hans-Peter Tony
Journal:  Arthritis Rheum       Date:  2006-08

7.  CD19+CD24hiCD38hi B cells maintain regulatory T cells while limiting TH1 and TH17 differentiation.

Authors:  Fabian Flores-Borja; Anneleen Bosma; Dorothy Ng; Venkat Reddy; Michael R Ehrenstein; David A Isenberg; Claudia Mauri
Journal:  Sci Transl Med       Date:  2013-02-20       Impact factor: 17.956

8.  The efficacy and safety of B-cell depletion with anti-CD20 monoclonal antibody in adults with chronic immune thrombocytopenic purpura.

Authors:  Nichola Cooper; Roberto Stasi; Susanna Cunningham-Rundles; Michael A Feuerstein; John P Leonard; Sergio Amadori; James B Bussel
Journal:  Br J Haematol       Date:  2004-04       Impact factor: 6.998

9.  CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients.

Authors:  Paul A Blair; Lina Yassin Noreña; Fabian Flores-Borja; David J Rawlings; David A Isenberg; Michael R Ehrenstein; Claudia Mauri
Journal:  Immunity       Date:  2010-01-14       Impact factor: 31.745

10.  Regulatory B cells are induced by gut microbiota-driven interleukin-1β and interleukin-6 production.

Authors:  Elizabeth C Rosser; Kristine Oleinika; Silvia Tonon; Ronan Doyle; Anneleen Bosma; Natalie A Carter; Kathryn A Harris; Simon A Jones; Nigel Klein; Claudia Mauri
Journal:  Nat Med       Date:  2014-10-19       Impact factor: 53.440
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  11 in total

1.  Ins and Outs of Antibodies.

Authors:  Sudhir Gupta
Journal:  J Clin Immunol       Date:  2016-05-12       Impact factor: 8.317

2.  New Method for the Expansion of Highly Purified Human Regulatory Granzyme B-Expressing B Cells.

Authors:  Mélanie Chesneau; Hoa Le Mai; Sophie Brouard
Journal:  Methods Mol Biol       Date:  2021

Review 3.  B Regulatory Cells: Players in Pregnancy and Early Life.

Authors:  Ana Esteve-Solé; Yiyi Luo; Alexandru Vlagea; Ángela Deyà-Martínez; Jordi Yagüe; Ana María Plaza-Martín; Manel Juan; Laia Alsina
Journal:  Int J Mol Sci       Date:  2018-07-19       Impact factor: 5.923

4.  Analysis of the dysregulation between regulatory B and T cells (Breg and Treg) in human immunodeficiency virus (HIV)-infected patients.

Authors:  Carolina Gutiérrez; Jacobo Lopez-Abente; Verónica Pérez-Fernández; Adrián Prieto-Sánchez; Rafael Correa-Rocha; Santiago Moreno-Guillen; María-Ángeles Muñoz-Fernández; Marjorie Pion
Journal:  PLoS One       Date:  2019-03-27       Impact factor: 3.240

5.  IL-10 Producing B Cells Dampen Protective T Cell Response and Allow Chlamydia muridarum Infection of the Male Genital Tract.

Authors:  Leonardo R Sanchez; Gloria J Godoy; Melisa Gorosito Serrán; Maria L Breser; Facundo Fiocca Vernengo; Pablo Engel; Ruben D Motrich; Adriana Gruppi; Virginia E Rivero
Journal:  Front Immunol       Date:  2019-03-01       Impact factor: 7.561

6.  Sequential CD19 and BCMA-specific CAR T-cell treatment elicits sustained remission of relapsed and/or refractory myeloma.

Authors:  Lingzhi Yan; Su Qu; Jingjing Shang; Xiaolan Shi; Liqing Kang; Nan Xu; Mingqing Zhu; Jin Zhou; Song Jin; Weiqin Yao; Ying Yao; Guanghua Chen; Huirong Chang; Xiaming Zhu; Lei Yu; Depei Wu; Chengcheng Fu
Journal:  Cancer Med       Date:  2020-12-23       Impact factor: 4.452

7.  The survival and function of IL-10-producing regulatory B cells are negatively controlled by SLAMF5.

Authors:  Lihi Radomir; Matthias P Kramer; Michal Perpinial; Nofar Schottlender; Stav Rabani; Keren David; Anna Wiener; Hadas Lewinsky; Shirly Becker-Herman; Rina Aharoni; Ron Milo; Claudia Mauri; Idit Shachar
Journal:  Nat Commun       Date:  2021-03-25       Impact factor: 14.919

8.  A Combination of Deworming and Prime-Boost Vaccination Regimen Restores Efficacy of Vaccination Against Influenza in Helminth-Infected Mice.

Authors:  Nadine Stetter; Wiebke Hartmann; Marie-Luise Brunn; Stephanie Stanelle-Bertram; Gülsah Gabriel; Minka Breloer
Journal:  Front Immunol       Date:  2021-12-21       Impact factor: 7.561

Review 9.  Regulatory B cells: the cutting edge of immune tolerance in kidney transplantation.

Authors:  Bo Peng; Yingzi Ming; Cheng Yang
Journal:  Cell Death Dis       Date:  2018-01-25       Impact factor: 8.469

10.  Generation of Human Breg-Like Phenotype with Regulatory Function In Vitro with Bacteria-Derived Oligodeoxynucleotides.

Authors:  Jorge Gallego-Valle; Verónica Astrid Pérez-Fernández; Rafael Correa-Rocha; Marjorie Pion
Journal:  Int J Mol Sci       Date:  2018-06-12       Impact factor: 5.923
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