Literature DB >> 27008020

Operating on Genomic Ranges Using BEDOPS.

Shane Neph1, Alex P Reynolds1, M Scott Kuehn2, John A Stamatoyannopoulos3,4,5.   

Abstract

The bulk of modern genomics research includes, in part, analyses of large data sets, such as those derived from high resolution, high-throughput experiments, that make computations challenging. The BEDOPS toolkit offers a broad spectrum of fundamental analysis capabilities to query, operate on, and compare quantitatively genomic data sets of any size and number. The toolkit facilitates the construction of complex analysis pipelines that remain efficient in both memory and time by chaining together combinations of its complementary components. The principal utilities accept raw or compressed data in a flexible format, and they provide built-in features to expedite parallel computations.

Keywords:  Algorithm; Bioinformatics; Compression; Genomics; Overlap; Parallelization; Sequencing

Mesh:

Year:  2016        PMID: 27008020     DOI: 10.1007/978-1-4939-3578-9_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  5 in total

1.  Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci.

Authors:  Karsten B Sieber; Anna Batorsky; Kyle Siebenthall; Kelly L Hudkins; Jeff D Vierstra; Shawn Sullivan; Aakash Sur; Michelle McNulty; Richard Sandstrom; Alex Reynolds; Daniel Bates; Morgan Diegel; Douglass Dunn; Jemma Nelson; Michael Buckley; Rajinder Kaul; Matthew G Sampson; Jonathan Himmelfarb; Charles E Alpers; Dawn Waterworth; Shreeram Akilesh
Journal:  J Am Soc Nephrol       Date:  2019-02-13       Impact factor: 10.121

2.  UROPA: a tool for Universal RObust Peak Annotation.

Authors:  Maria Kondili; Annika Fust; Jens Preussner; Carsten Kuenne; Thomas Braun; Mario Looso
Journal:  Sci Rep       Date:  2017-06-01       Impact factor: 4.379

3.  Maize RNA PolIV affects the expression of genes with nearby TE insertions and has a genome-wide repressive impact on transcription.

Authors:  Cristian Forestan; Silvia Farinati; Riccardo Aiese Cigliano; Alice Lunardon; Walter Sanseverino; Serena Varotto
Journal:  BMC Plant Biol       Date:  2017-10-12       Impact factor: 4.215

4.  CTCF-dependent chromatin boundaries formed by asymmetric nucleosome arrays with decreased linker length.

Authors:  Christopher T Clarkson; Emma A Deeks; Ralph Samarista; Hulkar Mamayusupova; Victor B Zhurkin; Vladimir B Teif
Journal:  Nucleic Acids Res       Date:  2019-12-02       Impact factor: 16.971

5.  Ecological divergence and hybridization of Neotropical Leishmania parasites.

Authors:  Frederik Van den Broeck; Nicholas J Savill; Hideo Imamura; Mandy Sanders; Ilse Maes; Sinclair Cooper; David Mateus; Marlene Jara; Vanessa Adaui; Jorge Arevalo; Alejandro Llanos-Cuentas; Lineth Garcia; Elisa Cupolillo; Michael Miles; Matthew Berriman; Achim Schnaufer; James A Cotton; Jean-Claude Dujardin
Journal:  Proc Natl Acad Sci U S A       Date:  2020-09-21       Impact factor: 11.205

  5 in total

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