Literature DB >> 27007921

Correction: Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus.

Chantal E Hargreaves, Chisako Iriyama, Matthew J J Rose-Zerilli, Sietse Q Nagelkerke, Khiyam Hussain, Rosalind Ganderton, Charlotte Lee, Lee R Machado, Edward J Hollox, Helen Parker, Kate V Latham, Taco W Kuijpers, Kathleen N Potter, Sarah E Coupland, Andrew Davies, Michael Stackpole, Melanie Oates, Andrew R Pettitt, Martin J Glennie, Mark S Cragg, Jonathan C Strefford.   

Abstract

Entities:  

Year:  2016        PMID： 27007921      PMCID： PMC4805206          DOI： 10.1371/journal.pone.0145040

Source DB:  PubMed          Journal:  PLoS One        ISSN： 1932-6203            Impact factor:   3.240


× No keyword cloud information.
Fig 4 is incorrect. The figure is an older version, which contains an inaccurate summary of data. The authors have provided a corrected version here.
Fig 4

Performance of FcγR -targeted probes in healthy donors.

(A) Probe binding performance was assessed by measuring the mean and SD of individual probes across our cohort of 164. Probes are represented in locus order. A normalised peak height ratio of 1 represents a diploid copy number. Error bars represent the mean +/- SD and the SD is shown above each probe. (B) Copy number regions (CNRs) 1 and 2 in healthy donors with observed numbers of duplication and deletion events. One donor showed CNV likely to include two duplications; one of the distal part containing FCGR2C and FCGR3B (CNR1) on one chromosome and one of the proximal part containing FCGR3A and FCGR2C (CNR2) on the other chromosome. * Probes in which the variability is a result of known genomic SNPs targeted by the probe.

Performance of FcγR -targeted probes in healthy donors.

(A) Probe binding performance was assessed by measuring the mean and SD of individual probes across our cohort of 164. Probes are represented in locus order. A normalised peak height ratio of 1 represents a diploid copy number. Error bars represent the mean +/- SD and the SD is shown above each probe. (B) Copy number regions (CNRs) 1 and 2 in healthy donors with observed numbers of duplication and deletion events. One donor showed CNV likely to include two duplications; one of the distal part containing FCGR2C and FCGR3B (CNR1) on one chromosome and one of the proximal part containing FCGR3A and FCGR2C (CNR2) on the other chromosome. * Probes in which the variability is a result of known genomic SNPs targeted by the probe.
  1 in total

1.  Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus.

Authors:  Chantal E Hargreaves; Chisako Iriyama; Matthew J J Rose-Zerilli; Sietse Q Nagelkerke; Khiyam Hussain; Rosalind Ganderton; Charlotte Lee; Lee R Machado; Edward J Hollox; Helen Parker; Kate V Latham; Taco W Kuijpers; Kathleen N Potter; Sarah E Coupland; Andrew Davies; Michael Stackpole; Melanie Oates; Andrew R Pettitt; Martin J Glennie; Mark S Cragg; Jonathan C Strefford
Journal:  PLoS One       Date:  2015-11-06       Impact factor: 3.240
  1 in total
  1 in total

1.  Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format.

Authors:  Khiyam Hussain; Chantal E Hargreaves; Tania F Rowley; Joshua M Sopp; Kate V Latham; Pallavi Bhatta; John Sherington; Rona M Cutler; David P Humphreys; Martin J Glennie; Jonathan C Strefford; Mark S Cragg
Journal:  Front Immunol       Date:  2019-03-07       Impact factor: 7.561
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.