Literature DB >> 27006742

The Chikungunya virus: An emerging US pathogen.

Thomas M Nappe1, Craig M Chuhran2, Steven A Johnson1.   

Abstract

BACKGROUND: The Chikungunya (CHIK) virus was recently reported by the CDC to have spread to the United States. We report an early documented case of CHIK from the state of Pennsylvania after a patient recently returned from Haiti in June of 2014.
METHODS: A 39-year-old man presented to the emergency department complaining of fever, fatigue, polyarthralgias and a diffuse rash for two days. Four days before, he returned from a mission trip to Haiti and reported that four of his accompanying friends had also become ill. A CHIK antibody titer was obtained and it was found to be positive. During his hospital stay, he responded well to supportive care, including anti-inflammatories, intravenous hydration and anti-emetics.
RESULTS: His condition improved within two days and he was ultimately discharged home.
CONCLUSIONS: Manifestations of CHIK can be similar to Dengue fever, which is transmitted by the same species of mosquito, and occasionally as a co-infection. Clinicians should include Chikungunya virus in their differential diagnosis of patients who present with fever, polyarthralgia and rash with a recent history of travel to endemic areas, including those within the United States.

Entities:  

Keywords:  Arbovirus; Chikungunya virus; Mosquito-borne disease; Polyarthralgia

Year:  2016        PMID: 27006742      PMCID: PMC4786503          DOI: 10.5847/wjem.j.1920-8642.2016.01.012

Source DB:  PubMed          Journal:  World J Emerg Med        ISSN: 1920-8642


  4 in total

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2.  Management of travelers with fever and exanthema, notably dengue and chikungunya infections.

Authors:  Patrick Hochedez; Ana Canestri; Amélie Guihot; Ségolène Brichler; François Bricaire; Eric Caumes
Journal:  Am J Trop Med Hyg       Date:  2008-05       Impact factor: 2.345

3.  Infection with chikungunya virus in Italy: an outbreak in a temperate region.

Authors:  G Rezza; L Nicoletti; R Angelini; R Romi; A C Finarelli; M Panning; P Cordioli; C Fortuna; S Boros; F Magurano; G Silvi; P Angelini; M Dottori; M G Ciufolini; G C Majori; A Cassone
Journal:  Lancet       Date:  2007-12-01       Impact factor: 79.321

4.  Notes from the field: Transmission of chikungunya virus in the continental United States--Florida, 2014.

Authors:  Katherine Kendrick; Danielle Stanek; Carina Blackmore
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2014-12-05       Impact factor: 17.586

  4 in total
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1.  Novel Mutations in nsP2 Abolish Chikungunya Virus-Induced Transcriptional Shutoff and Make the Virus Less Cytopathic without Affecting Its Replication Rates.

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Journal:  J Virol       Date:  2019-02-05       Impact factor: 5.103

Review 2.  Molecular Virology of Chikungunya Virus.

Authors:  I Frolov; E I Frolova
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  2 in total

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