Literature DB >> 27005450

Autonomous immunity in mucosal epithelial cells: fortifying the barrier against infection.

Karen F Ross1, Mark C Herzberg2.   

Abstract

Mucosal epithelial cells express an autonomous innate immune response that controls the overgrowth of invaded bacteria, mitigates the harmful effects of the bacteria carried within, and does not rely on other external arms of the immune response. Epithelial cell autonomous innate immunity "respects" the social biology of invading bacteria to achieve symbiosis, and is the primary protective mechanism against pathogens. Published by Elsevier Masson SAS.

Entities:  

Keywords:  Antimicrobial proteins; Cell signaling; Infection; Innate immunity; Mucosal epithelium

Mesh:

Year:  2016        PMID: 27005450      PMCID: PMC4884473          DOI: 10.1016/j.micinf.2016.03.008

Source DB:  PubMed          Journal:  Microbes Infect        ISSN: 1286-4579            Impact factor:   2.700


  129 in total

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