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Literature DB >> 27005444

New Insights into the Regulation of Heterochromatin.

Jiyong Wang¹, Sharon T Jia¹, Songtao Jia².

Abstract

All living organisms are constantly exposed to stresses from internal biological processes and surrounding environments, which induce many adaptive changes in cellular physiology and gene expression programs. Unexpectedly, constitutive heterochromatin, which is generally associated with the stable maintenance of gene silencing, is also dynamically regulated in response to stimuli. In this review we discuss the mechanism of constitutive heterochromatin assembly, its dynamic nature, and its responses to environmental changes.

Entities: Chemical Disease Gene Species

Keywords: constitutive heterochromatin; dynamics; epigenetic adaptation; stress

Mesh：

Substances：
Heterochromatin
Histones

Year: 2016 PMID： 27005444 PMCID： PMC4842111 DOI： 10.1016/j.tig.2016.02.005

Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639

105 in total

Review 1. Histone methylation in transcriptional control.

Authors: Tony Kouzarides
Journal: Curr Opin Genet Dev Date: 2002-04 Impact factor: 5.578

2. The significance of responses of the genome to challenge.

Authors: B McClintock
Journal: Science Date: 1984-11-16 Impact factor: 47.728

3. Swi6/HP1 recruits a JmjC domain protein to facilitate transcription of heterochromatic repeats.

Authors: Martin Zofall; Shiv I S Grewal
Journal: Mol Cell Date: 2006-06-09 Impact factor: 17.970

4. Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.

Authors: Dale K Shumaker; Thomas Dechat; Alexander Kohlmaier; Stephen A Adam; Matthew R Bozovsky; Michael R Erdos; Maria Eriksson; Anne E Goldman; Satya Khuon; Francis S Collins; Thomas Jenuwein; Robert D Goldman
Journal: Proc Natl Acad Sci U S A Date: 2006-05-31 Impact factor: 11.205

5. Position effect variegation at the mating-type locus of fission yeast: a cis-acting element inhibits covariegated expression of genes in the silent and expressed domains.

Authors: N Ayoub; I Goldshmidt; A Cohen
Journal: Genetics Date: 1999-06 Impact factor: 4.562

6. Discrete roles of the Spc1 kinase and the Atf1 transcription factor in the UV response of Schizosaccharomyces pombe.

Authors: G Degols; P Russell
Journal: Mol Cell Biol Date: 1997-06 Impact factor: 4.272

Review 7. HP1a: a structural chromosomal protein regulating transcription.

Authors: Joel C Eissenberg; Sarah C R Elgin
Journal: Trends Genet Date: 2014-02-17 Impact factor: 11.639

8. Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage.

Authors: H Renauld; O M Aparicio; P D Zierath; B L Billington; S K Chhablani; D E Gottschling
Journal: Genes Dev Date: 1993-07 Impact factor: 11.361

9. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast.

Authors: A Hecht; T Laroche; S Strahl-Bolsinger; S M Gasser; M Grunstein
Journal: Cell Date: 1995-02-24 Impact factor: 41.582

10. Epigenome rejuvenation: HP1β mobility as a measure of pluripotent and senescent chromatin ground states.

Authors: Maria Manukyan; Prim B Singh
Journal: Sci Rep Date: 2014-04-25 Impact factor: 4.379

49 in total

Review 1. Computational approaches for inferring 3D conformations of chromatin from chromosome conformation capture data.

Authors: Dario Meluzzi; Gaurav Arya
Journal: Methods Date: 2019-08-27 Impact factor: 3.608

New Insights into the Regulation of Heterochromatin.

Review 1. Histone methylation in transcriptional control.

2. The significance of responses of the genome to challenge.

3. Swi6/HP1 recruits a JmjC domain protein to facilitate transcription of heterochromatic repeats.

4. Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.

5. Position effect variegation at the mating-type locus of fission yeast: a cis-acting element inhibits covariegated expression of genes in the silent and expressed domains.

6. Discrete roles of the Spc1 kinase and the Atf1 transcription factor in the UV response of Schizosaccharomyces pombe.

Review 7. HP1a: a structural chromosomal protein regulating transcription.

8. Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage.

9. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast.

10. Epigenome rejuvenation: HP1β mobility as a measure of pluripotent and senescent chromatin ground states.

Review 1. Computational approaches for inferring 3D conformations of chromatin from chromosome conformation capture data.

Review 2. Epigenetic control of gene regulation during development and disease: A view from the retina.

3. SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation.

4. Role of nucleosome positioning in 3D chromatin organization and loop formation.

5. PTEN as a Guardian of the Genome: Pathways and Targets.

6. Cohesin Impedes Heterochromatin Assembly in Fission Yeast Cells Lacking Pds5.

Review 7. Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity.

8. Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance.

9. The interplay between H2A.Z and H3K9 methylation in regulating HP1α binding to linker histone-containing chromatin.

10. DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation.