Literature DB >> 27003571

[Cardiovascular risks of androgen deprivation therapy for prostate cancer].

K Miller1.   

Abstract

Androgen deprivation therapy (ADT) is the standard treatment for metastatic prostate cancer. It has increasingly been used in other stages of the disease as well. Besides well-known side effects caused by the lack of testosterone (impotency, osteoporosis, fatigue, loss of muscle mass), an increase of cardiovascular (CV) morbidity and mortality has recently been discussed in association with ADT. Cardiovascular side effects cannot be sufficiently explained by low testosterone levels. This review gives an overview of the recent literature, interprets the results, and offers clinical consequences.

Entities:  

Keywords:  Androgen deprivation therapy; Cardio vascular events; GnRH antagonists; LHRH agonists; Prostate cancer

Mesh:

Substances:

Year:  2016        PMID: 27003571     DOI: 10.1007/s00120-015-0021-1

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  26 in total

1.  Androgen deprivation therapy and cardiovascular harm: are all men created equal?

Authors:  Derek J Rosario; Liam Bourke; Nancy L Keating
Journal:  Eur Urol       Date:  2013-11-20       Impact factor: 20.096

2.  Androgen-deprivation therapy in treatment of prostate cancer and risk of myocardial infarction and stroke: a nationwide Danish population-based cohort study.

Authors:  Christina G Jespersen; Mette Nørgaard; Michael Borre
Journal:  Eur Urol       Date:  2013-02-12       Impact factor: 20.096

3.  Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysis.

Authors:  J Seidenfeld; D J Samson; V Hasselblad; N Aronson; P C Albertsen; C L Bennett; T J Wilt
Journal:  Ann Intern Med       Date:  2000-04-04       Impact factor: 25.391

4.  Influence of androgen deprivation therapy on all-cause mortality in men with high-risk prostate cancer and a history of congestive heart failure or myocardial infarction.

Authors:  Paul L Nguyen; Ming-Hui Chen; Joshua A Beckman; Clair J Beard; Neil E Martin; Toni K Choueiri; Jim C Hu; Karen E Hoffman; Daniel E Dosoretz; Brian J Moran; Sharon A Salenius; Michelle H Braccioforte; Philip W Kantoff; Anthony V D'Amico; Ronald D Ennis
Journal:  Int J Radiat Oncol Biol Phys       Date:  2011-06-25       Impact factor: 7.038

5.  Human peripheral blood mononuclear cells express gonadotropin-releasing hormone (GnRH), GnRH receptor, and interleukin-2 receptor gamma-chain messenger ribonucleic acids that are regulated by GnRH in vitro.

Authors:  H F Chen; E B Jeung; M Stephenson; P C Leung
Journal:  J Clin Endocrinol Metab       Date:  1999-02       Impact factor: 5.958

6.  Cardiovascular morbidity associated with gonadotropin releasing hormone agonists and an antagonist.

Authors:  Peter C Albertsen; Laurence Klotz; Bertrand Tombal; James Grady; Tine K Olesen; Jan Nilsson
Journal:  Eur Urol       Date:  2013-11-01       Impact factor: 20.096

Review 7.  Adverse effects of androgen deprivation therapy and strategies to mitigate them.

Authors:  Paul L Nguyen; Shabbir M H Alibhai; Shehzad Basaria; Anthony V D'Amico; Philip W Kantoff; Nancy L Keating; David F Penson; Derek J Rosario; Bertrand Tombal; Matthew R Smith
Journal:  Eur Urol       Date:  2014-08-02       Impact factor: 20.096

8.  Androgen deprivation therapy increases cardiovascular morbidity in men with prostate cancer.

Authors:  Christopher S Saigal; John L Gore; Tracey L Krupski; Janet Hanley; Matthias Schonlau; Mark S Litwin
Journal:  Cancer       Date:  2007-10-01       Impact factor: 6.860

9.  Influence of androgen suppression therapy for prostate cancer on the frequency and timing of fatal myocardial infarctions.

Authors:  Anthony V D'Amico; James W Denham; Juanita Crook; Ming-Hui Chen; Samuel Z Goldhaber; David S Lamb; David Joseph; Keen-Hun Tai; Shawn Malone; Charles Ludgate; Allison Steigler; Philip W Kantoff
Journal:  J Clin Oncol       Date:  2007-06-10       Impact factor: 44.544

10.  Cardiovascular mortality and duration of androgen deprivation for locally advanced prostate cancer: analysis of RTOG 92-02.

Authors:  Jason A Efstathiou; Kyounghwa Bae; William U Shipley; Gerald E Hanks; Miljenko V Pilepich; Howard M Sandler; Matthew R Smith
Journal:  Eur Urol       Date:  2008-01-15       Impact factor: 20.096

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  1 in total

1.  Androgen-Deprivation Therapy and Cardiovascular Disease Risk - The Role of Exercise in Prostate Cancer Treatment.

Authors:  Bradley Wall
Journal:  Front Oncol       Date:  2016-09-19       Impact factor: 6.244

  1 in total

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