Michelle M Hui1, Denis Wakefield1,2, Ilesh Patel3, Erin Cvejic4, Peter J McCluskey1,2,5, John H Chang1,6,7. 1. a School of Medical Science , Faculty of Medicine (UNSW) , Kensington , New South Wales , Australia. 2. b Department of Ophthalmology , St Vincent's Hospital , Darlinghurst , New South Wales , Australia. 3. c Hornsby Eye Specialists , Hornsby , New South Wales , Australia. 4. e School of Psychiatry, University of New South Wales , Kensington , New South Wales , Australia. 5. g Save Sight Institute, University of Sydney , Sydney , New South Wales , Australia. 6. d Retina and Vitreous Centre , Strathfield , New South Wales , Australia. 7. f Marsden Eye Specialists , Parramatta , New South Wales , Australia.
Abstract
PURPOSE: To assess the vision-related (VR) and health-related (HR) quality-of-life (QoL) of patients with uveitis. METHODS: In total, 60 patients with uveitis, 81 patients with diabetic retinopathy (DR), and 70 healthy subjects completed the National Eye Institute Visual Functioning Questionnaire and the Medical Outcome Study 36-Item Short Form. RESULTS: Patients with uveitis reported lower HR- and VR-QoL than healthy subjects (p<0.05) and lower VR-QoL (p<0.001) than patients with DR. For patients with uveitis, multiple linear regression analyses indicated that lower HR-QoL scores were predicted by younger age (p<0.01), while lower VR-QoL scores were predicted by poorer visual acuity (p<0.001), ocular comorbidities (p<0.05), and female sex (p<0.05). CONCLUSIONS: Patients with uveitis have significantly poorer VR- and HR-QoL than healthy control subjects. Uveitis has a more debilitating impact on VR-QoL than DR.
PURPOSE: To assess the vision-related (VR) and health-related (HR) quality-of-life (QoL) of patients with uveitis. METHODS: In total, 60 patients with uveitis, 81 patients with diabetic retinopathy (DR), and 70 healthy subjects completed the National Eye Institute Visual Functioning Questionnaire and the Medical Outcome Study 36-Item Short Form. RESULTS:Patients with uveitis reported lower HR- and VR-QoL than healthy subjects (p<0.05) and lower VR-QoL (p<0.001) than patients with DR. For patients with uveitis, multiple linear regression analyses indicated that lower HR-QoL scores were predicted by younger age (p<0.01), while lower VR-QoL scores were predicted by poorer visual acuity (p<0.001), ocular comorbidities (p<0.05), and female sex (p<0.05). CONCLUSIONS:Patients with uveitis have significantly poorer VR- and HR-QoL than healthy control subjects. Uveitis has a more debilitating impact on VR-QoL than DR.
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