Literature DB >> 27000212

Neurotrophic factors in Parkinson's disease are regulated by exercise: Evidence-based practice.

Paula Grazielle Chaves da Silva1, Daniel Desidério Domingues1, Litia Alves de Carvalho1, Silvana Allodi2, Clynton Lourenço Correa3.   

Abstract

We carried out a qualitative review of the literature on the influence of forced or voluntary exercise in Parkinson's Disease (PD)-induced animals, to better understand neural mechanisms and the role of neurotrophic factors (NFs) involved in the improvement of motor behavior. A few studies indicated that forced or voluntary exercise may promote neuroprotection, through upregulation of NF expression, against toxicity of drugs that simulate PD. Forced training, such as treadmill exercise and forced-limb use, adopted in most studies, in addition to voluntary exercise on a running wheel are suitable methods for NFs upregulation.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Animal model; Exercise; Neuroprotective agents; Parkinson's disease

Mesh：

Substances：

Year:  2016        PMID： 27000212     DOI： 10.1016/j.jns.2016.02.017

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN： 0022-510X            Impact factor:   3.181


  19 in total

1.  Treadmill Exercise Prevents Increase of Neuroinflammation Markers Involved in the Dopaminergic Damage of the 6-OHDA Parkinson's Disease Model.

Authors:  Caroline Cristiano Real; Priscila Crespo Garcia; Luiz R G Britto
Journal:  J Mol Neurosci       Date:  2017-08-11       Impact factor: 3.444

Review 2.  Exercise as a Positive Modulator of Brain Function.

Authors:  Karim A Alkadhi
Journal:  Mol Neurobiol       Date:  2017-05-02       Impact factor: 5.590

3.  Timed Release of Cerebrolysin Using Drug-Loaded Titanate Nanospheres Reduces Brain Pathology and Improves Behavioral Functions in Parkinson's Disease.

Authors:  Asya Ozkizilcik; Aruna Sharma; Dafin F Muresanu; José V Lafuente; Z Ryan Tian; Ranjana Patnaik; Herbert Mössler; Hari S Sharma
Journal:  Mol Neurobiol       Date:  2018-01       Impact factor: 5.590

4.  Whole body vibration and treadmill training in Parkinson's disease rehabilitation: effects on energy cost and recovery phases.

Authors:  Silvia Corbianco; Gabriella Cavallini; Giacomo Baldereschi; Maria Chiara Carboncini; Francesca Lidia Fiamingo; Paolo Bongioanni; Marco Dini
Journal:  Neurol Sci       Date:  2018-09-19       Impact factor: 3.307

Review 5.  Microbiota and Neurological Disorders: A Gut Feeling.

Authors:  Walter H Moos; Douglas V Faller; David N Harpp; Iphigenia Kanara; Julie Pernokas; Whitney R Powers; Kosta Steliou
Journal:  Biores Open Access       Date:  2016-05-01

6.  Aerobic Exercise Preserves Olfaction Function in Individuals with Parkinson's Disease.

Authors:  Anson B Rosenfeldt; Tanujit Dey; Jay L Alberts
Journal:  Parkinsons Dis       Date:  2016-11-23

Review 7.  Exercise-induced increase in brain-derived neurotrophic factor in human Parkinson's disease: a systematic review and meta-analysis.

Authors:  Mark A Hirsch; Erwin E H van Wegen; Mark A Newman; Patricia C Heyn
Journal:  Transl Neurodegener       Date:  2018-03-20       Impact factor: 8.014

8.  Parkinson Disease: An Evolutionary Perspective.

Authors:  Pedro J Garcia-Ruiz; Alberto J Espay
Journal:  Front Neurol       Date:  2017-05-01       Impact factor: 4.003

9.  An 8-Week Low-Intensity Progressive Cycling Training Improves Motor Functions in Patients with Early-Stage Parkinson's Disease.

Authors:  Hsiu Chen Chang; Chin Song Lu; Wei Da Chiou; Chiung Chu Chen; Yi Hsin Weng; Ya Ju Chang
Journal:  J Clin Neurol       Date:  2018-04       Impact factor: 3.077

Review 10.  Exercise-Induced Neuroprotection of the Nigrostriatal Dopamine System in Parkinson's Disease.

Authors:  Lijuan Hou; Wei Chen; Xiaoli Liu; Decai Qiao; Fu-Ming Zhou
Journal:  Front Aging Neurosci       Date:  2017-11-03       Impact factor: 5.750
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