Literature DB >> 26999706

Herquline A, produced by Penicillium herquei FKI-7215, exhibits anti-influenza virus properties.

Takuya Chiba1, Yukihiro Asami1,2, Takuya Suga1, Yoshihiro Watanabe1, Takayuki Nagai1,2, Fumitaka Momose1,2, Kenichi Nonaka1,2, Masato Iwatsuki1,2, Haruki Yamada1,2, Satoshi Ōmura2, Kazuro Shiomi1,2.   

Abstract

In the course of screening for new anti-influenza virus antibiotics, we isolated herquline A from a culture broth of the fungus, Penicillium herquei FKI-7215. Herquline A inhibited replication of influenza virus A/PR/8/34 strain in a dose-dependent manner without exhibiting cytotoxicity against several human cell lines. It did not inhibit the viral neuraminidase.

Entities:  

Keywords:  A/PR/8/34 strain; Penicillium herquei; herquline A; influenza virus

Mesh:

Substances:

Year:  2016        PMID: 26999706     DOI: 10.1080/09168451.2016.1162084

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  4 in total

Review 1.  Oxidative Cyclization in Natural Product Biosynthesis.

Authors:  Man-Cheng Tang; Yi Zou; Kenji Watanabe; Christopher T Walsh; Yi Tang
Journal:  Chem Rev       Date:  2016-12-12       Impact factor: 60.622

2.  Piperazine ring formation by a single-module NRPS and cleavage by an α-KG-dependent nonheme iron dioxygenase in brasiliamide biosynthesis.

Authors:  Bochuan Yuan; Dong Liu; Xin Guan; Yunchen Yan; Jianping Zhang; Yiping Zhang; Donghui Yang; Ming Ma; Wenhan Lin
Journal:  Appl Microbiol Biotechnol       Date:  2020-05-21       Impact factor: 4.813

3.  Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

Authors:  J Houbraken; S Kocsubé; C M Visagie; N Yilmaz; X-C Wang; M Meijer; B Kraak; V Hubka; K Bensch; R A Samson; J C Frisvad
Journal:  Stud Mycol       Date:  2020-06-27       Impact factor: 16.097

4.  Diketoacetonylphenalenone, Derived from Hawaiian Volcanic Soil-Associated Fungus Penicillium herquei FT729, Regulates T Cell Activation via Nuclear Factor-κB and Mitogen-Activated Protein Kinase Pathway.

Authors:  Hyun-Su Lee; Jae Sik Yu; Ki Hyun Kim; Gil-Saeng Jeong
Journal:  Molecules       Date:  2020-11-17       Impact factor: 4.411

  4 in total

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