Angelin A Jebamalar1, Agiesh K Balakrishnapillai2, Narayanan Parmeswaran3, Pooja Dhiman1, Soundravally Rajendiran1. 1. a Department of Biochemistry , Jawaharlal Institute of Postgraduate Medical Education and Research , Puducherry , India . 2. b School of Chemical and Biotechnology, SASTRA University , Thanjavur , India , and. 3. c Department of Paediatrics , Jawaharlal Institute of Postgraduate Medical Education and Research , Puducherry , India.
Abstract
OBJECTIVES: To evaluate the diagnostic role of cerebrospinal fluid (CSF) ferritin and albumin index (AI = CSF albumin/serum albumin × 1000) in differentiating acute bacterial meningitis (ABM) from acute viral meningitis (AVM) in children. METHODS: The study included 42 cases each of ABM and AVM in pediatric age group. Receiver operating characteristic (ROC) analysis was carried out for CSF ferritin and AI. Binary logistic regression was also done. RESULTS: CSF ferritin and AI were found significantly higher in ABM compared to AVM. Model obtained using AI and CSF ferritin along with conventional criteria is better than existing models.
OBJECTIVES: To evaluate the diagnostic role of cerebrospinal fluid (CSF) ferritin and albumin index (AI = CSF albumin/serum albumin × 1000) in differentiating acute bacterial meningitis (ABM) from acute viral meningitis (AVM) in children. METHODS: The study included 42 cases each of ABM and AVM in pediatric age group. Receiver operating characteristic (ROC) analysis was carried out for CSF ferritin and AI. Binary logistic regression was also done. RESULTS: CSF ferritin and AI were found significantly higher in ABM compared to AVM. Model obtained using AI and CSF ferritin along with conventional criteria is better than existing models.
Entities:
Keywords:
Albumin index; bacterial meningitis; diagnostic model; ferritin; viral meningitis
Authors: A Pormohammad; S Lashkarbolouki; T Azimi; P Gholizadeh; N Bostanghadiri; H Safari; S Armin; N Mohtavinejad; F Fallah Journal: New Microbes New Infect Date: 2019-08-29