Literature DB >> 26998643

Ulbactins F and G, Polycyclic Thiazoline Derivatives with Tumor Cell Migration Inhibitory Activity from Brevibacillus sp.

Yasuhiro Igarashi1, Daisuke Asano1, Masashi Sawamura1, Yasuko In2, Toshimasa Ishida2, Masaya Imoto3.   

Abstract

Two new structurally unique compounds bearing a nitrogen- and sulfur-containing tricyclic ring system, ulbactin F (1) and its diastereomeric isomer ulbactin G (2), were isolated from the culture extract of a sponge-derived Brevibacillus sp. The structures and absolute configurations of 1 and 2 were determined by NMR analysis and X-ray crystallographic analysis. These compounds inhibit the migration of tumor cells in the submicromolar to micromolar range.

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Year:  2016        PMID： 26998643     DOI： 10.1021/acs.orglett.6b00531

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  8 in total

1.  Pyochelin Biosynthetic Metabolites Bind Iron and Promote Growth in Pseudomonads Demonstrating Siderophore-like Activity.

Authors:  Anna R Kaplan; Djamaladdin G Musaev; William M Wuest
Journal:  ACS Infect Dis       Date:  2021-02-12       Impact factor: 5.084

2.  Cyclopropeniminium Ions Exhibit Unique Reactivity Profiles with Bioorthogonal Phosphines.

Authors:  Tyler K Heiss; Jennifer A Prescher
Journal:  J Org Chem       Date:  2019-05-28       Impact factor: 4.354

3.  Pan-genome analysis identifies intersecting roles for Pseudomonas specialized metabolites in potato pathogen inhibition.

Authors:  Alba Pacheco-Moreno; Francesca L Stefanato; Jonathan J Ford; Christine Trippel; Simon Uszkoreit; Laura Ferrafiat; Lucia Grenga; Ruth Dickens; Nathan Kelly; Alexander Dh Kingdon; Liana Ambrosetti; Sergey A Nepogodiev; Kim C Findlay; Jitender Cheema; Martin Trick; Govind Chandra; Graham Tomalin; Jacob G Malone; Andrew W Truman
Journal:  Elife       Date:  2021-12-31       Impact factor: 8.140

Review 4.  Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms.

Authors:  Huawei Zhang; Ziping Zhao; Hong Wang
Journal:  Mar Drugs       Date:  2017-03-10       Impact factor: 5.118

5.  New Thiazoline-Tetralin Derivatives and Biological Activity Evaluation.

Authors:  Gülhan Turan-Zitouni; Leyla Yurttaş; Aouatef Tabbi; Gülşen Akalın Çiftçi; Halide Edip Temel; Zafer Asım Kaplancıklı
Journal:  Molecules       Date:  2018-01-10       Impact factor: 4.411

6.  Total Synthesis of Mutanobactins A, B from the Human Microbiome: Macrocyclization and Thiazepanone Assembly in a Single Step.

Authors:  Moritz E Hansen; Samuel O Yasmin; Susanne Wolfrum; Erick M Carreira
Journal:  Angew Chem Int Ed Engl       Date:  2022-06-10       Impact factor: 16.823

Review 7.  The diversity and utility of arylthiazoline and aryloxazoline siderophores: challenges of total synthesis.

Authors:  Karolina Kamińska; Andrzej Mular; Evgenia Olshvang; Nils Metzler Nolte; Henryk Kozłowski; Elżbieta Wojaczyńska; Elżbieta Gumienna-Kontecka
Journal:  RSC Adv       Date:  2022-09-07       Impact factor: 4.036

Review 8.  β-Hydroxy sulfides and their syntheses.

Authors:  Mokgethwa Bruce Marakalala; Edwin M Mmutlane; Henok H Kinfe
Journal:  Beilstein J Org Chem       Date:  2018-07-05       Impact factor: 2.883
  8 in total

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