Literature DB >> 26996124

Self-assembly of a 5-fluorouracil-dipeptide hydrogel.

Yuan Sun1, Jonah A Kaplan, Aileen Shieh, Hui-Lung Sun, Carlo M Croce, Mark W Grinstaff, Jon R Parquette.   

Abstract

The self-assembly of 5-fluorouracil dilysine conjugates into self-supporting hydrogels, comprised of entangled nanofibers or rigid nanotubes with diameters of 10 and 16 nm, respectively, is reported. The rate of release of 5-Fu from the conjugates was highly dependent on concentration in solution, whereas, release from the fully formed hydrogels was significantly slower. The 5-Fu conjugate also exhibited promising in vitro cytotoxicity against human tumor cell lines A549, H460 and H23.

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Year:  2016        PMID： 26996124     DOI： 10.1039/c6cc01195k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Molecular design and synthesis of self-assembling camptothecin drug amphiphiles.

Authors:  Andrew G Cheetham; Yi-An Lin; Ran Lin; Honggang Cui
Journal:  Acta Pharmacol Sin       Date:  2017-03-06       Impact factor: 6.150

Review 2.  Ultrashort Peptide Self-Assembly: Front-Runners to Transport Drug and Gene Cargos.

Authors:  Seema Gupta; Indu Singh; Ashwani K Sharma; Pradeep Kumar
Journal:  Front Bioeng Biotechnol       Date:  2020-05-29

3.  Synthetic CO2-fixation enzyme cascades immobilized on self-assembled nanostructures that enhance CO2/O2 selectivity of RubisCO.

Authors:  Sriram Satagopan; Yuan Sun; Jon R Parquette; F Robert Tabita
Journal:  Biotechnol Biofuels       Date:  2017-07-06       Impact factor: 6.040

4.  Threading carbon nanotubes through a self-assembled nanotube.

Authors:  Mingyang Ji; McKensie L Mason; David A Modarelli; Jon R Parquette
Journal:  Chem Sci       Date:  2019-08-01       Impact factor: 9.825

Review 5.  Peptide-Protein Interactions: From Drug Design to Supramolecular Biomaterials.

Authors:  Andrea Caporale; Simone Adorinni; Doriano Lamba; Michele Saviano
Journal:  Molecules       Date:  2021-02-25       Impact factor: 4.411

6.  Ion-Triggered Hydrogels Self-Assembled from Statistical Copolypeptides.

Authors:  Bing Wu; Saltuk B Hanay; Scott D Kimmins; Sally-Ann Cryan; Daniel Hermida Merino; Andreas Heise
Journal:  ACS Macro Lett       Date:  2022-02-16       Impact factor: 6.903

Review 7.  Applications of self-assembling ultrashort peptides in bionanotechnology.

Authors:  Ming Ni; Shuangmu Zhuo
Journal:  RSC Adv       Date:  2019-01-08       Impact factor: 4.036

8.  Fabrication and Evaluation of Gellan Gum/Hyaluronic Acid Hydrogel for Retinal Tissue Engineering Biomaterial and the Influence of Substrate Stress Relaxation on Retinal Pigment Epithelial Cells.

Authors:  Jina Youn; Joo Hee Choi; Sumi Lee; Wonchan Lee; Seong Won Lee; Wooyoup Kim; Youngeun Song; Nomin-Erdene Tumursukh; Jeong Eun Song; Gilson Khang
Journal:  Molecules       Date:  2022-08-27       Impact factor: 4.927

9.  Honey-based hydrogel: In vitro and comparative In vivo evaluation for burn wound healing.

Authors:  Reham F El-Kased; Reham I Amer; Dalia Attia; M M Elmazar
Journal:  Sci Rep       Date:  2017-08-29       Impact factor: 4.379
  9 in total

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