| Literature DB >> 26996007 |
Pornphimol Meesakul, Thunwadee Ritthiwigrom, Sarot Cheenpracha, Tawanun Sripisut, Wisanu Maneerat, Theeraphan Machan, Surat Laphookhieo.
Abstract
The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC₅₀ values of 2.48 and 6.63 µM, respectively.Entities:
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Year: 2016 PMID： 26996007
Source DB: PubMed Journal: Nat Prod Commun ISSN： 1555-9475 Impact factor: 0.986