A Fillion1, P Ortega-Deballon2, S Al-Samman2, A Briault3, C Brigand4, S Deguelte5, A Germain6, Y Hansmann7, E Pelascini8, C Rabaud9, P Chavanet10, L Piroth10. 1. Infectious Diseases Department, University Hospital of Dijon, BP 97908, 21000 Dijon, France. Electronic address: aurelie.fillion@ch-chalon71.fr. 2. Digestive and Surgical Oncology Department, University Hospital of Dijon, BP 97908, 21000 Dijon, France. 3. Department of Pneumology, University Hospital of Grenoble, CS 10217, 38043 Grenoble cedex 09, France. 4. Department of Digestive Surgery, University Hospital of Strasbourg, 67098 Strasbourg, France. 5. Department of Digestive Surgery, University Hospital of Reims, Robert-Debré Hospital, avenue General-Koening, 51092 Reims cedex, France. 6. Department of Digestive, Hepatobiliary, and Endocrine Surgery, University Hospital of Nancy, Hôpitaux de Brabois, bâtiment Philippe-Canton, allée du Morvan, 54511 Vandœuvre-lès-Nancy cedex, France. 7. Infectious Disease Department, University Hospital of Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France. 8. Department of Digestive Surgery, University Hospital of Lyon, Hôpital Édouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France. 9. Infectious Diseases Department, University Hospital of Nancy, Hôpitaux de Brabois, bâtiment Philippe-Canton, allée du Morvan, 54511 Vandœuvre-lès-Nancy cedex, France. 10. Infectious Diseases Department, University Hospital of Dijon, BP 97908, 21000 Dijon, France.
Abstract
OBJECTIVE: Abdominal tuberculosis is a rare disease. The clinical and radiological manifestations are non-specific and the diagnosis is difficult. Our objective was to describe the characteristics and treatment of patients presenting with abdominal tuberculosis in a low-incidence country. PATIENTS AND METHODS: We reviewed the clinical, diagnostic, treatment, and outcome features of patients presenting with abdominal tuberculosis diagnosed by bacteriological and/or histological results and managed in five French university hospitals from January 2000 to December 2009. RESULTS: We included 21 patients. The mean diagnostic delay was 13 months. Twelve patients (57%) came from a low-incidence area and only two had a known immunosuppressed condition. Eighteen patients (86%) presented with abdominal symptoms. The main organs involved were the peritoneum (n=14, 66%), the mesenteric lymph nodes (n=13, 62%), and the bowel (n=7, 33%). Sixteen patients (76%) underwent surgery, including two in an emergency setting. Seventeen patients (81%) received six months or more of anti-tuberculosis treatment. Finally, 16 patients (76%) had a positive outcome. CONCLUSION: New diagnostic procedures, and especially molecular biology, may help diagnose unusual clinical presentations of tuberculosis. Invasive procedures are frequently necessary to obtain samples but also for the treatment of digestive involvement.
OBJECTIVE:Abdominal tuberculosis is a rare disease. The clinical and radiological manifestations are non-specific and the diagnosis is difficult. Our objective was to describe the characteristics and treatment of patients presenting with abdominal tuberculosis in a low-incidence country. PATIENTS AND METHODS: We reviewed the clinical, diagnostic, treatment, and outcome features of patients presenting with abdominal tuberculosis diagnosed by bacteriological and/or histological results and managed in five French university hospitals from January 2000 to December 2009. RESULTS: We included 21 patients. The mean diagnostic delay was 13 months. Twelve patients (57%) came from a low-incidence area and only two had a known immunosuppressed condition. Eighteen patients (86%) presented with abdominal symptoms. The main organs involved were the peritoneum (n=14, 66%), the mesenteric lymph nodes (n=13, 62%), and the bowel (n=7, 33%). Sixteen patients (76%) underwent surgery, including two in an emergency setting. Seventeen patients (81%) received six months or more of anti-tuberculosis treatment. Finally, 16 patients (76%) had a positive outcome. CONCLUSION: New diagnostic procedures, and especially molecular biology, may help diagnose unusual clinical presentations of tuberculosis. Invasive procedures are frequently necessary to obtain samples but also for the treatment of digestive involvement.
Authors: Hicham ELmajdoubi; Mariam El Yahiyaoui; Marouane Baiss; Mohamed Bouzroud; El Mehdi Aboulfeth; Mohammed Najih; Sidi Mohamed Bouchentouf; Hakim ELkaoui; Ahmed Bounaim Journal: Case Rep Surg Date: 2021-06-30