Kristin Melheim Strand1, Magnus O Dahlseng1, Stian Lydersen2, Torstein B Rø3, Ane-Kristine Finbråten1, Reidun B Jahnsen4, Guro L Andersen5, Torstein Vik1. 1. Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. 2. The Regional Centre for Child and Adolescent Mental Health, NTNU, Trondheim, Norway. 3. Department of Pediatrics, St Olavs University Hospital, Trondheim, Norway. 4. Oslo University Hospital, Oslo, Norway. 5. The Cerebral Palsy Register of Norway, Vestfold Hospital Trust, Tønsberg, Norway.
Abstract
AIM: To describe growth in infancy and early childhood in children with cerebral palsy (CP). METHOD: One hundred and four children with CP born at minimum 36 weeks' gestation in 2002 to 2010 were included. Prospectively collected growth data were requested from public health clinics. We calculated standard deviation (SD) scores (z-scores) for weight and height for 12 set age points for each child from birth to 5 years, and for head circumference from birth to 12 months. RESULTS: Children with CP had normal growth in weight and height if they were born non-small for gestational age (non-SGA) or had mild motor impairments (i.e. Gross Motor Function Classification System [GMFCS] I-II), whereas children born SGA or with severe motor impairments (GMFCS III-V) had reduced growth (p<0.001). Children with feeding difficulties in infancy had reduced growth in weight and height throughout early childhood, while children without feeding difficulties had normal growth. Head circumference growth decreased most severely among children born SGA, who had mean z-scores of -3.0 (95% confidence interval [CI] -3.7 to -2.2) at 1 year. INTERPRETATION: Children with mild CP had normal growth in weight and height until 5 years, and in head circumference during infancy. Feeding difficulties in infancy and being born SGA were strongly associated with reduced growth.
AIM: To describe growth in infancy and early childhood in children with cerebral palsy (CP). METHOD: One hundred and four children with CP born at minimum 36 weeks' gestation in 2002 to 2010 were included. Prospectively collected growth data were requested from public health clinics. We calculated standard deviation (SD) scores (z-scores) for weight and height for 12 set age points for each child from birth to 5 years, and for head circumference from birth to 12 months. RESULTS:Children with CP had normal growth in weight and height if they were born non-small for gestational age (non-SGA) or had mild motor impairments (i.e. Gross Motor Function Classification System [GMFCS] I-II), whereas children born SGA or with severe motor impairments (GMFCS III-V) had reduced growth (p<0.001). Children with feeding difficulties in infancy had reduced growth in weight and height throughout early childhood, while children without feeding difficulties had normal growth. Head circumference growth decreased most severely among children born SGA, who had mean z-scores of -3.0 (95% confidence interval [CI] -3.7 to -2.2) at 1 year. INTERPRETATION:Children with mild CP had normal growth in weight and height until 5 years, and in head circumference during infancy. Feeding difficulties in infancy and being born SGA were strongly associated with reduced growth.
Authors: Elisabeth C McGowan; Abbot R Laptook; Jean Lowe; Myriam Peralta-Carcelen; Dhuly Chowdhury; Rosemary D Higgins; Susan R Hintz; Betty R Vohr Journal: J Pediatr Date: 2019-09-06 Impact factor: 4.406
Authors: Maria de Las Mercedes Ruiz Brunner; Eduardo Cuestas; Florian Heinen; Andreas Sebastian Schroeder Journal: Sci Rep Date: 2022-02-03 Impact factor: 4.379