| Literature DB >> 26992059 |
Louise Nielsen1,2, Florence Canouï-Poitrine3,4, Jean-Philippe Jais5,6, Djamal Dahmane1, Pablo Bartolucci7,8,9, Bouteina Bentaarit1, Justine Gellen-Dautremer7, Philippe Remy1,2, Tomek Kofman1,2, Marie Matignon1,2, Caroline Suberbielle10, Christian Jacquelinet11,12, Orianne Wagner-Ballon13,14, Dil Sahali1,2, Philippe Lang1,2, Thibaud Damy15,16, Frédéric Galactéros7,8,9, Philippe Grimbert1,2, Anoosha Habibi7,8,9, Vincent Audard1,2.
Abstract
We performed a retrospective study to assess the changes in clinical, biological and heart echocardiographic parameters in 32 sickle cell disease (SCD) patients beginning haemodialysis. Acute SCD-related complications were similar at 6 months before and 6 months after the initiation of haemodialysis. Median haemoglobin level did not change significantly, but the need for blood transfusions increased (P < 0·001). The 5-year incidence of death was higher in SCD patients (P < 0·0001). The 5-year likelihood of receiving a renal graft was lower in SCD patients (P = 0·022). Our findings suggest that SCD patients have poorer survival and a lower likelihood of receiving a renal graft.Entities:
Keywords: dialysis; kidney; sickle cell disease; survival; vaso-occlusive crises
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Year: 2016 PMID： 26992059 DOI： 10.1111/bjh.14040
Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998