Literature DB >> 26990130

Treg subsets in inflammatory bowel disease and colorectal carcinoma: Characteristics, role, and therapeutic targets.

Egbert H van Herk1, Anje A Te Velde1.   

Abstract

T regulatory cells (Tregs) play an important role in the regulation of autoimmunity, autoinflammation, allergic diseases, infection, and the tumor environment. Different subsets are characterized that use a number of regulatory mechanisms. Tregs can influence the progression of inflammatory bowel disease and the development of colorectal cancer. Knowledge of Tregs and their regulatory mechanisms can provide new targets for therapeutic intervention.
© 2016 The Authors Journal of Gastroenterology and Hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

Entities:  

Keywords:  CRC; FOXP3; IBD; Tr1; Treg; therapy

Mesh：

Substances：

Year:  2016        PMID： 26990130     DOI： 10.1111/jgh.13342

Source DB:  PubMed          Journal:  J Gastroenterol Hepatol        ISSN： 0815-9319            Impact factor:   4.029


  11 in total

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4.  The Prognostic Value of Immune Factors in the Tumor Microenvironment of Penile Squamous Cell Carcinoma.

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Journal:  Front Immunol       Date:  2018-06-11       Impact factor: 7.561

Review 5.  Activation of Resolution Pathways to Prevent and Fight Chronic Inflammation: Lessons From Asthma and Inflammatory Bowel Disease.

Authors:  Cindy Barnig; Tjitske Bezema; Philip C Calder; Anne Charloux; Nelly Frossard; Johan Garssen; Oliver Haworth; Ksenia Dilevskaya; Francesca Levi-Schaffer; Evelyne Lonsdorfer; Marca Wauben; Aletta D Kraneveld; Anje A Te Velde
Journal:  Front Immunol       Date:  2019-07-23       Impact factor: 7.561

Review 6.  Inflammaging, an Imbalanced Immune Response That Needs to Be Restored for Cancer Prevention and Treatment in the Elderly.

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Journal:  Cells       Date:  2021-09-28       Impact factor: 6.600

7.  Inflammation and tumor progression: signaling pathways and targeted intervention.

Authors:  Huakan Zhao; Lei Wu; Guifang Yan; Yu Chen; Mingyue Zhou; Yongzhong Wu; Yongsheng Li
Journal:  Signal Transduct Target Ther       Date:  2021-07-12

8.  Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease.

Authors:  Linyan Zhou; Dongyan Liu; Ying Xie; Xinjie Yao; Yan Li
Journal:  Gut Liver       Date:  2019-03-15       Impact factor: 4.519

9.  Protective Role of Fecal Microbiota Transplantation on Colitis and Colitis-Associated Colon Cancer in Mice Is Associated With Treg Cells.

Authors:  Zitao Wang; Wenjie Hua; Chen Li; Hao Chang; Ran Liu; Yangyue Ni; Hongzhi Sun; Yangyang Li; Xinyue Wang; Min Hou; Yu Liu; Zhipeng Xu; Minjun Ji
Journal:  Front Microbiol       Date:  2019-11-12       Impact factor: 5.640

10.  Standardized Fraction of Turbinaria ornata Alleviates Dextran Sulfate Sodium-Induced Chronic Colitis in C57BL/6 Mice via Upregulation of FOXP3+ Regulatory T Cells.

Authors:  Na-Hyun Kim; Seon Min Lee; Yun Na Kim; You-Jin Jeon; Jeong-Doo Heo; Eun Ju Jeong; Jung-Rae Rho
Journal:  Biomolecules       Date:  2020-10-20
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