Literature DB >> 26989651

Coexistence of tinnitus and hyperacusis in individuals with auditory dys-synchrony: A single case study.

K N Megha1, Sugathan Adithya1, K P Keerthana1, Sreeraj Konadath1.   

Abstract

Certain clinical pathologies affecting the ear and hearing mechanism may co-exist. It is necessary to probe in detail into such conditions so that the pathophysiology is well understood. This research paper through a single case study tries to explain the probable pathophysiology behind coexistence of three different clinical conditions namely auditory dys-synchrony, hyperacusis and tinnitus. These conditions are common in the clinics, but the coexistence of all the three is rare and demands explanation beyond what is available in the literature. The assumed model highlights involvement of the outer hair cell's motor function in the cochlea along with the auditory central gain mechanism to explain possible pathophysiology behind coexistence of the three conditions. This model will provide insight into the probable link between the contribution of peripheral and central structures of hearing in generating tinnitus and hyperacusis in individuals having auditory dys-synchrony.

Entities:  

Keywords:  Auditory dys-synchrony; hyperacusis; tinnitus

Year:  2016        PMID: 26989651      PMCID: PMC4761586          DOI: 10.5582/irdr.2015.01044

Source DB:  PubMed          Journal:  Intractable Rare Dis Res        ISSN: 2186-3644


  22 in total

1.  Cochlear implants in five cases of auditory neuropathy: postoperative findings and progress.

Authors:  J K Shallop; A Peterson; G W Facer; L B Fabry; C L Driscoll
Journal:  Laryngoscope       Date:  2001-04       Impact factor: 3.325

Review 2.  Modulation of hair cell efferents.

Authors:  Eric Wersinger; Paul Albert Fuchs
Journal:  Hear Res       Date:  2010-12-25       Impact factor: 3.208

3.  Cochlear implantation of auditory neuropathy.

Authors:  P G Trautwein; Y S Sininger; R Nelson
Journal:  J Am Acad Audiol       Date:  2000-06       Impact factor: 1.664

4.  Prevalence and audiological characteristics in individuals with auditory neuropathy/auditory dys-synchrony.

Authors:  U Ajith Kumar; M M Jayaram
Journal:  Int J Audiol       Date:  2006-06       Impact factor: 2.117

Review 5.  Auditory neuropathy/dys-synchrony and its perceptual consequences.

Authors:  Gary Rance
Journal:  Trends Amplif       Date:  2005

6.  Single-neuron labeling and chronic cochlear pathology. III. Stereocilia damage and alterations of threshold tuning curves.

Authors:  M C Liberman; L W Dodds
Journal:  Hear Res       Date:  1984-10       Impact factor: 3.208

7.  Clinical findings for a group of infants and young children with auditory neuropathy.

Authors:  G Rance; D E Beer; B Cone-Wesson; R K Shepherd; R C Dowell; A M King; F W Rickards; G M Clark
Journal:  Ear Hear       Date:  1999-06       Impact factor: 3.570

8.  Auditory neuropathy with preserved cochlear microphonics and secondary loss of otoacoustic emissions.

Authors:  P Deltenre; A L Mansbach; C Bozet; F Christiaens; P Barthelemy; D Paulissen; T Renglet
Journal:  Audiology       Date:  1999 Jul-Aug

9.  Does type I afferent neuron dysfunction reveal itself through lack of efferent suppression?

Authors:  C I Berlin; L J Hood; R P Cecola; D F Jackson; P Szabo
Journal:  Hear Res       Date:  1993-02       Impact factor: 3.208

10.  Auditory neuropathy/dyssynchrony: its diagnosis and management.

Authors:  Charles I Berlin; Thierry Morlet; Linda J Hood
Journal:  Pediatr Clin North Am       Date:  2003-04       Impact factor: 3.278

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