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Literature DB >> 26987913

Healing a Heart Through Genetic Intervention.

Jeanne James¹, Jeffrey Robbins².

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Year: 2016 PMID： 26987913 PMCID： PMC4801122 DOI： 10.1161/CIRCRESAHA.116.308468

Source DB: PubMed Journal: Circ Res ISSN： 0009-7330 Impact factor: 17.367

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References

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17 in total

1. Transgenic over-expression of a motor protein at high levels results in severe cardiac pathology.

Authors: J James; H Osinska; T E Hewett; T Kimball; R Klevitsky; S Witt; D G Hall; J Gulick; J Robbins
Journal: Transgenic Res Date: 1999-02 Impact factor: 2.788

2. CRISPR provides acquired resistance against viruses in prokaryotes.

Authors: Rodolphe Barrangou; Christophe Fremaux; Hélène Deveau; Melissa Richards; Patrick Boyaval; Sylvain Moineau; Dennis A Romero; Philippe Horvath
Journal: Science Date: 2007-03-23 Impact factor: 47.728

3. Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus.

Authors: Florian T Merkle; Werner M Neuhausser; David Santos; Eivind Valen; James A Gagnon; Kristi Maas; Jackson Sandoe; Alexander F Schier; Kevin Eggan
Journal: Cell Rep Date: 2015-04-30 Impact factor: 9.423

4. Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart.

Authors: W K Jones; I L Grupp; T Doetschman; G Grupp; H Osinska; T E Hewett; G Boivin; J Gulick; W A Ng; J Robbins
Journal: J Clin Invest Date: 1996-10-15 Impact factor: 14.808

Review 5. In vivo definition of a cardiac specific promoter and its potential utility in remodeling the heart.

Authors: J Robbins; J Palermo; H Rindt
Journal: Ann N Y Acad Sci Date: 1995-03-27 Impact factor: 5.691

6. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Authors: Christopher E Nelson; Chady H Hakim; David G Ousterout; Pratiksha I Thakore; Eirik A Moreb; Ruth M Castellanos Rivera; Sarina Madhavan; Xiufang Pan; F Ann Ran; Winston X Yan; Aravind Asokan; Feng Zhang; Dongsheng Duan; Charles A Gersbach
Journal: Science Date: 2015-12-31 Impact factor: 47.728

Healing a Heart Through Genetic Intervention.

1. Transgenic over-expression of a motor protein at high levels results in severe cardiac pathology.

2. CRISPR provides acquired resistance against viruses in prokaryotes.

3. Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus.

4. Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart.

Review 5. In vivo definition of a cardiac specific promoter and its potential utility in remodeling the heart.

6. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

7. Cardiac phenotype determines survival in Duchenne muscular dystrophy.

8. An in vivo analysis of transcriptional elements in the mouse alpha-myosin heavy chain gene promoter.

9. Adeno-associated viral (AAV) vectors do not efficiently target muscle satellite cells.

Review 10. Genome-editing Technologies for Gene and Cell Therapy.