Literature DB >> 26987332

Obstructive Sleep Apnea Is Related to Increased Arterial Stiffness in Ultrasound Speckle-Tracking Analysis.

I Tuleta1, D Skowasch2, J Krycki2, C Pizarro2, C Hammerstingl2, M Weber2, N Schahab2, G Nickenig2, C Schaefer2, S Pingel2.   

Abstract

Obstructive sleep apnea (OSA) is an independent risk factor for atherosclerosis. The aim of our study was to determine arterial stiffness in OSA patients by means of the ultrasound speckle-tracking-based method. Twenty six OSA patients and 17 control subjects were enrolled in the study. The speckle-tracking-based analysis of carotid artery included circumferential strains, circumferential strain rates, radial displacement, and radial strain rates. We found that the global average circumferential strains, circumferential strain rates, and radial displacement were significantly lower in OSA patients compared to controls (2.19 ± 0.30 % vs. 4.17 ± 0.33 %, 0.22 ± 0.03 l/s vs. 0.31 ± 0.02 l/s, 0.10 ± 0.01 mm vs. 0.16 ± 0.02 mm, respectively, p < 0.05 for all). There were no significant differences in radial strain rates between the groups (0.32 ± 0.04 % vs. 0.33 ± 0.01 %). We conclude that OSA is associated with an increased arterial stiffness.

Entities:  

Keywords:  Functional vessel damage; Intermittent nocturnal hypoxia; Vascular incompliance; Vessel wall deformation; Vessel wall motion

Mesh:

Year:  2016        PMID: 26987332     DOI: 10.1007/5584_2016_215

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  2 in total

1.  Carotid strain measurement in patients with pseudoxanthoma elasticum - Hint for a different pathomechanism?

Authors:  Sebastian Gorgonius Passon; Viviane Küllmar; Anna Katharina Blatzheim; Kristin Solveig Pausewang; Max Jonathan Stumpf; Doris Hendig; Martin Gliem; Simon Pingel; Robert Schueler; Dirk Skowasch; Najib Schahab; Georg Nickenig; Christian Alexander Schaefer
Journal:  Intractable Rare Dis Res       Date:  2018-02

2.  Impairment of vascular strain in patients with obstructive sleep apnea.

Authors:  Max Jonathan Stumpf; Christian Alexander Schaefer; Jan Krycki; Robert Schueler; Carmen Pizarro; Georg Nickenig; Martin Steinmetz; Dirk Skowasch; Izabela Tuleta
Journal:  PLoS One       Date:  2018-02-28       Impact factor: 3.240

  2 in total

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