Literature DB >> 26986809

Radiation Duration in Women with Cervical Cancer Treated with Primary Chemoradiation: A Population-Based Analysis.

Ana I Tergas1,2,3, Alfred I Neugut2,3,4, Ling Chen1, William M Burke1, Dawn L Hershman2,3,4, Jason D Wright1,2,3.   

Abstract

This study examines factors associated with prolonged radiation duration and its impact on survival in women with cervical cancer treated with primary chemoradiation. Women in the National Cancer Database with stage IB2-IVA cervical cancer from 2003 to 2011 who received radiation and chemotherapy were included. Of 7209 women, who met inclusion criteria, 3401 (47.1%) and 3808 (52.8%) completed radiation in ≤ 8 and > 8 weeks, respectively. There was no overall survival difference for radiation duration ≤ 8 vs. > 8 weeks. Sensitivity analyses showed that inferior overall survival is only seen with radiation duration of > 10-12 weeks.

Entities:  

Keywords:  Cervical Cancer; Health Sciences Research; Treatment

Mesh：

Year:  2016        PMID： 26986809      PMCID： PMC4834975          DOI： 10.3109/07357907.2015.1131291

Source DB:  PubMed          Journal:  Cancer Invest        ISSN： 0735-7907            Impact factor:   2.176


  30 in total

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Authors:  J F Fowler; M J Lindstrom
Journal:  Int J Radiat Oncol Biol Phys       Date:  1992       Impact factor: 7.038

2.  The effect of treatment duration in the local control of cervix cancer.

Authors:  A Fyles; T J Keane; M Barton; J Simm
Journal:  Radiother Oncol       Date:  1992-12       Impact factor: 6.280

3.  Socioeconomic status and health: how education, income, and occupation contribute to risk factors for cardiovascular disease.

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Journal:  Am J Public Health       Date:  1992-06       Impact factor: 9.308

4.  Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases.

Authors:  R A Deyo; D C Cherkin; M A Ciol
Journal:  J Clin Epidemiol       Date:  1992-06       Impact factor: 6.437

5.  Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer.

Authors:  M Morris; P J Eifel; J Lu; P W Grigsby; C Levenback; R E Stevens; M Rotman; D M Gershenson; D G Mutch
Journal:  N Engl J Med       Date:  1999-04-15       Impact factor: 91.245

6.  Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer.

Authors:  P G Rose; B N Bundy; E B Watkins; J T Thigpen; G Deppe; M A Maiman; D L Clarke-Pearson; S Insalaco
Journal:  N Engl J Med       Date:  1999-04-15       Impact factor: 91.245

7.  The adverse effect of treatment prolongation in cervical carcinoma.

Authors:  D G Petereit; J N Sarkaria; R Chappell; J F Fowler; T J Hartmann; T J Kinsella; J A Stitt; B R Thomadsen; D A Buchler
Journal:  Int J Radiat Oncol Biol Phys       Date:  1995-07-30       Impact factor: 7.038

8.  The influence of treatment time on outcome for squamous cell cancer of the uterine cervix treated with radiation: a patterns-of-care study.

Authors:  R M Lanciano; T F Pajak; K Martz; G E Hanks
Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-02-15       Impact factor: 7.038

9.  Overall treatment time in advanced cervical carcinomas: a critical parameter in treatment outcome.

Authors:  T Girinsky; A Rey; B Roche; C Haie; A Gerbaulet; H Randrianarivello; D Chassagne
Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-12-01       Impact factor: 7.038

10.  Carcinoma of the uterine cervix. I. Impact of prolongation of overall treatment time and timing of brachytherapy on outcome of radiation therapy.

Authors:  C A Perez; P W Grigsby; H Castro-Vita; M A Lockett
Journal:  Int J Radiat Oncol Biol Phys       Date:  1995-07-30       Impact factor: 7.038
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  2 in total

1.  [Substantial advantage of CT-planned HDR brachytherapy for cervical cancer patients compared to a historical series with regard to local control and toxicity?]

Authors:  Simone Marnitz
Journal:  Strahlenther Onkol       Date:  2017-03       Impact factor: 3.621

2.  Comparison of Definitive Cervical Cancer Management With Chemotherapy and Radiation Between Two Centers With Variable Resources and Opportunities for Improved Treatment.

Authors:  Francis Adumata Asamoah; Joel Yarney; Aba Scott; Verna Vanderpuye; Zhigang Yuan; Daniel C Fernandez; Michael E Montejo; Mervin Agyeman; Samuel Ntiamoah Boateng; Kwabena Anarfi; Charles Aidoo; Mian M Shahzad; Jing-Yi Chern; Hye-Sook Chon; Robert M Wenham; Kosj Yamoah; Kamran A Ahmed
Journal:  JCO Glob Oncol       Date:  2020-10
  2 in total

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