Literature DB >> 26983053

Three new cembranoids from the Bornean soft coral Nephthea sp.

Takahiro Ishii1, Takashi Kamada1, Charles S Vairappan1.   

Abstract

Three new cembranoid diterpenes, 10-hydroxy-nephthenol acetate (1), 7,8-epoxy-10-hydroxy-nephthenol acetate (2), and 6-acetoxy-7,8-epoxy-10-hydroxy-nephthenol acetate (3), along with a known compound, 6-acetoxy-7,8-epoxy-nephthenol acetate (4), were isolated from the Bornean soft coral Nephthea sp. Antibacterial and anticancer activities were exhibited by compounds 1 and 2 against Staphylococcus aureus (ATCC 6538)/Escherichia coli (ATCC 13311) and Hela/MCF-7, respectively.

Entities:  

Keywords:  Bornean soft coral; Cembranoid; Nephthea sp.; Nephtheidae

Mesh：

Substances：

Year:  2016        PMID： 26983053     DOI： 10.1080/10286020.2016.1145670

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN： 1028-6020            Impact factor:   1.569


  2 in total

Review 1.  Cembranoids of Soft Corals: Recent Updates and Their Biological Activities.

Authors:  Marsya Yonna Nurrachma; Deamon Sakaraga; Ahmad Yogi Nugraha; Siti Irma Rahmawati; Asep Bayu; Linda Sukmarini; Akhirta Atikana; Anggia Prasetyoputri; Fauzia Izzati; Mega Ferdina Warsito; Masteria Yunovilsa Putra
Journal:  Nat Prod Bioprospect       Date:  2021-04-22

2.  Bioactive Cembranoids from the Soft Coral Genus Sinularia sp. in Borneo.

Authors:  Takashi Kamada; Min-Cheol Kang; Chin-Soon Phan; Intan Irna Zanil; You-Jin Jeon; Charles S Vairappan
Journal:  Mar Drugs       Date:  2018-03-21       Impact factor: 5.118
  2 in total

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