Gi Dong Lee1, Ho Cheol Kim2, Jung-Wan Yoo1, Seung Jun Lee1, Yu Ji Cho1, Kyungsoo Bae3, Jong Deog Lee1. 1. Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea.; Gyeongsang Institute of Health Sciences, Gyeongsang National University, Jinju, Republic of Korea. 2. Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea.; Gyeongsang Institute of Health Sciences, Gyeongsang National University, Jinju, Republic of Korea.. Electronic address: hochkim@gnu.ac.kr. 3. Gyeongsang Institute of Health Sciences, Gyeongsang National University, Jinju, Republic of Korea.; Department of Diagnostic Radiology, Gyeongsang National University School of Medicine, Jinju, Republic of Korea.
Abstract
PURPOSE: Patients who require mechanical ventilation (MV) may experience diaphragm atrophy, which may delay the discontinuation of MV. Here, we used computed tomographic (CT) scans to confirm this phenomenon. METHOD AND MATERIALS: Patients who underwent two chest CT scans while on MV were retrospectively evaluated. Diaphragm thickness was measured using a three-dimensional CT image processing program. RESULTS: Thirteen patients, including 8 men, who underwent 26 CT scans were assessed. The mean age was 67.8 ± 7.5 years. The interval between CT scans was 18.4 ± 14.9 days. The first CT scans revealed that the mean thicknesses of the left and right sides of the diaphragm were 3.8 ± 0.6 and 3.9 ± 0.8 mm, respectively (total: 7.7 ± 1.4 mm). These values were significantly reduced to 3.4 ± 0.6 and 3.5 ± 0.9 mm, respectively, (total: 6.9 ± 1.5 mm) after the second scan (P < .01). No significant change in body weight (57.3 ± 12.6 vs. 56.7 ± 11.6 kg) or body mass index (21.8 ± 5.1 vs. 21.6 ± 4.8 kg/m(2)) was observed. CONCLUSION: Computed tomography confirmed that diaphragm thickness was reduced in critically ill patients who underwent MV.
PURPOSE:Patients who require mechanical ventilation (MV) may experience diaphragm atrophy, which may delay the discontinuation of MV. Here, we used computed tomographic (CT) scans to confirm this phenomenon. METHOD AND MATERIALS: Patients who underwent two chest CT scans while on MV were retrospectively evaluated. Diaphragm thickness was measured using a three-dimensional CT image processing program. RESULTS: Thirteen patients, including 8 men, who underwent 26 CT scans were assessed. The mean age was 67.8 ± 7.5 years. The interval between CT scans was 18.4 ± 14.9 days. The first CT scans revealed that the mean thicknesses of the left and right sides of the diaphragm were 3.8 ± 0.6 and 3.9 ± 0.8 mm, respectively (total: 7.7 ± 1.4 mm). These values were significantly reduced to 3.4 ± 0.6 and 3.5 ± 0.9 mm, respectively, (total: 6.9 ± 1.5 mm) after the second scan (P < .01). No significant change in body weight (57.3 ± 12.6 vs. 56.7 ± 11.6 kg) or body mass index (21.8 ± 5.1 vs. 21.6 ± 4.8 kg/m(2)) was observed. CONCLUSION: Computed tomography confirmed that diaphragm thickness was reduced in critically illpatients who underwent MV.
Authors: Sung Woo Moon; Song Yee Kim; Ji Soo Choi; Ah Young Leem; Su Hwan Lee; Moo Suk Park; Young Sam Kim; Kyung Soo Chung Journal: Sci Rep Date: 2021-12-06 Impact factor: 4.379