Literature DB >> 26979509

[Thrombus aspiration in patients with acute myocardial infarction : Scientific evidence and guideline recommendations].

T Stiermaier1,2, S de Waha3,4, G Fürnau3,4, I Eitel3,4, H Thiele3,4, S Desch3,4.   

Abstract

Recent advances in percutaneous coronary intervention and antiplatelet therapy as well as faster door-to-balloon times have markedly improved the therapy of patients with acute myocardial infarction. However, impaired myocardial perfusion despite revascularization of the infarcted vessel remains an ongoing problem with high prognostic relevance. In initial clinical trials thrombus aspiration in addition to conventional percutaneous coronary intervention demonstrated benefits regarding coronary flow and myocardial perfusion and was therefore recommended in practice guidelines. These improvements in surrogate endpoints did not translate into a favorable clinical outcome in recent large-scale multicenter randomized trials investigating the routine use of thrombus aspiration in patients with acute myocardial infarction. Furthermore, an increased risk of stroke after thrombus aspiration raises safety concerns. Therefore, thrombus aspiration has been downgraded in the recent guideline updates. The current article reviews the evidence from clinical trials and the recommendations in practice guidelines regarding thrombus aspiration in acute myocardial infarction.

Entities:  

Keywords:  Acute myocardial infarction; Myocardial perfusion; No-reflow phenomenon; Percutaneous coronary intervention; Thrombus aspiration

Mesh：

Year:  2016        PMID： 26979509     DOI： 10.1007/s00059-016-4412-x

Source DB:  PubMed          Journal:  Herz        ISSN： 0340-9937            Impact factor:   1.443


  78 in total

1.  Effect of manual thrombus aspiration during primary percutaneous coronary intervention on infarct size: evaluation with cardiac computed tomography.

Authors:  Doo Sun Sim; Youngkeun Ahn; Yun-Hyeon Kim; Daun Lee; Hyun Ju Seon; Keun Ho Park; Hyun Ju Yoon; Nam Sik Yoon; Kye Hun Kim; Young Joon Hong; Hyung Wook Park; Ju Han Kim; Myung Ho Jeong; Jeong Gwan Cho; Jong Chun Park
Journal:  Int J Cardiol       Date:  2013-05-31       Impact factor: 4.164

2.  A randomized comparison of direct stenting with conventional stent implantation in selected patients with acute myocardial infarction.

Authors:  Christophe Loubeyre; Marie-Claude Morice; Thierry Lefèvre; Jean-François Piéchaud; Yves Louvard; Pierre Dumas
Journal:  J Am Coll Cardiol       Date:  2002-01-02       Impact factor: 24.094

3.  Incidence and distribution of occluded culprit arteries and impact of coronary collaterals on outcome in patients with non-ST-segment elevation myocardial infarction and early invasive treatment strategy.

Authors:  Philipp Bahrmann; Justus Rach; Steffen Desch; Gerhard C Schuler; Holger Thiele
Journal:  Clin Res Cardiol       Date:  2010-12-17       Impact factor: 5.460

4.  Distal microcirculatory protection during percutaneous coronary intervention in acute ST-segment elevation myocardial infarction: a randomized controlled trial.

Authors:  Gregg W Stone; John Webb; David A Cox; Bruce R Brodie; Mansoor Qureshi; Anna Kalynych; Mark Turco; Heinz P Schultheiss; Daniel Dulas; Barry D Rutherford; David Antoniucci; Mitchell W Krucoff; Raymond J Gibbons; Denise Jones; Alexandra J Lansky; Roxana Mehran
Journal:  JAMA       Date:  2005-03-02       Impact factor: 56.272

Review 5.  Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials.

Authors:  Ellen C Keeley; Judith A Boura; Cindy L Grines
Journal:  Lancet       Date:  2003-01-04       Impact factor: 79.321

6.  Randomized comparison of distal protection versus conventional treatment in primary percutaneous coronary intervention: the drug elution and distal protection in ST-elevation myocardial infarction (DEDICATION) trial.

Authors:  Henning Kelbaek; Christian J Terkelsen; Steffen Helqvist; Jens F Lassen; Peter Clemmensen; Lene Kløvgaard; Anne Kaltoft; Thomas Engstrøm; Hans E Bøtker; Kari Saunamäki; Lars R Krusell; Erik Jørgensen; Hans-Henrik T Hansen; Evald H Christiansen; Jan Ravkilde; Lars Køber; Klaus F Kofoed; Leif Thuesen
Journal:  J Am Coll Cardiol       Date:  2008-03-04       Impact factor: 24.094

7.  Effect of thrombus aspiration on infarct size and left ventricular function in high-risk patients with acute myocardial infarction treated by percutaneous coronary intervention. Results of a prospective controlled pilot study.

Authors:  Janusz Lipiecki; Séverine Monzy; Nicolas Durel; Florent Cachin; Pascal Chabrot; Aurelien Muliez; Dominique Morand; Jean Maublant; Jean Ponsonnaille
Journal:  Am Heart J       Date:  2009-02-04       Impact factor: 4.749

8.  Clinical efficacy of thrombus aspiration on 5-year clinical outcomes in patients with ST-segment elevation acute myocardial infarction undergoing percutaneous coronary intervention.

Authors:  Hiroki Watanabe; Hiroki Shiomi; Kenji Nakatsuma; Takeshi Morimoto; Tomohiko Taniguchi; Yutaka Furukawa; Yoshihisa Nakagawa; Minoru Horie; Takeshi Kimura; Takeshi Kimura; Ryuzo Sakata; Akira Marui; Mitsuo Matsuda; Hirokazu Mitsuoka; Masahiko Onoe; Yoshihisa Nakagawa; Kazuo Yamanaka; Hisayoshi Fujiwara; Yoshiki Takatsu; Nobuhisa Ohno; Ryuji Nohara; Tomoyuki Murakami; Teruki Takeda; Masakiyo Nobuyoshi; Masashi Iwabuchi; Michiya Hanyu; Ryozo Tatami; Tsutomu Matsushita; Manabu Shirotani; Noboru Nishiwaki; Toru Kita; Yutaka Furukawa; Yukikatsu Okada; Hiroshi Kato; Hiroshi Eizawa; Katsuhisa Is; Masaru Tanaka; Shogo Nakayama; Jong-Dae Lee; Akira Nakano; Takaaki Koshiji; Koichi Morioka; Akinori Takizawa; Mitsuomi Shimamoto; Fumio Yamazaki; Masaaki Takahashi; Junichiro Nishizawa; Minoru Horie; Hiroyuki Takashima; Takashi Tamura; Masaki Aota; Mamoru Takahashi; Takafumi Tabata; Chuwa Tei; Shuichi Hamasaki; Yutaka Imoto; Hiroyuki Yamamoto; Hirofumi Kambara; Osamu Doi; Katsuhiko Matsuda; Masafumi Nara; Kazuaki Mitsudo; Kazushige Kadota; Tatsuhiko Komiya; Shinji Miki; Tetsu Mizoguchi; Hiroyuki Nakajima; Hisao Ogawa; Seigo Sugiyama; Michio Kawasuji; Syuji Moriyama; Ryuichi Hattori; Takeshi Aoyama; Makoto Araki; Satoru Suwa; Keiichi Tanbara; Kumiko Kitagawa; Misato Yamauchi; Naoko Okamoto; Yumika Fujino; Saori Tezuka; Asuka Saeki; Miya Hanazawa; Yuki Sato; Chikako Hibi; Hitomi Sasae; Emi Takinami; Yuriko Uchida; Yuko Yamamoto; Satoko Nishida; Mai Yoshimoto; Sachiko Maeda; Izumi Miki; Saeko Minematsu; Mitsuru Abe; Hiroki Shiomi; Tomohisa Tada; Junichi Tazaki; Yoshihiro Kato; Mamoru Hayano; Akihiro Tokushige; Masahiro Natsuaki; Tetsu Nakajima
Journal:  J Am Heart Assoc       Date:  2015-06-15       Impact factor: 5.501

9.  Local Intracoronary Eptifibatide versus Mechanical Aspiration in Patients with Acute ST-Elevation Myocardial Infarction.

Authors:  Mohamed A Hamza; Ayman Galal; Salwa Suweilam; Mohamed Ismail
Journal:  Int J Vasc Med       Date:  2014-06-03

10.  Angiographic and Clinical Impact of Successful Manual Thrombus Aspiration in Diabetic Patients Undergoing Primary PCI.

Authors:  Mohamed Shehata
Journal:  Int J Vasc Med       Date:  2014-04-02
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  1 in total

1.  A new technique to salvage myocardium following the failure of thrombus aspiration in acute myocardial infarction: a case report.

Authors:  Daoyuan Si; Guohui Liu; Yaliang Tong; Cheng Zhang; Yuquan He
Journal:  BMC Cardiovasc Disord       Date:  2018-12-10       Impact factor: 2.298
  1 in total

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