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Correction: Renal Function Outcomes and Risk Factors for Risk Factors for Stage 3B Chronic Kidney Disease after Urinary Diversion in Patients with Muscle Invasive Bladder Cancer.

Shingo Hatakeyama, Takuya Koie, Takuma Narita, Shogo Hosogoe, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Chikara Ohyama.   

Abstract

Entities:  

Year:  2016        PMID: 26978781      PMCID: PMC4792434          DOI: 10.1371/journal.pone.0151742

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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The words “Risk Factors for” appear twice in the title of this article. The correct title is: Renal Function Outcomes and Risk Factors for Stage 3B Chronic Kidney Disease after Urinary Diversion in Patients with Muscle Invasive Bladder Cancer. The correct citation is: Hatakeyama S, Koie T, Narita T, Hosogoe S, Yamamoto H, Tobisawa Y, et al. (2016) Renal Function Outcomes and Risk Factors for Stage 3B Chronic Kidney Disease after Urinary Diversion in Patients with Muscle Invasive Bladder Cancer. PLoS ONE 11(2): e0149544. doi:10.1371/journal.pone.0149544 There are formatting errors in Table 1 and Table 3 of the published article. Please see the correct Table 1 and Table 3 here.
Table 1

Clinical and pathological patient characteristics.

All patientsMatched patients
IncontinentContinentP valueIncontinentContinentP value
n47683434
Ileal conduit / cutaneous ureterostomy, n =17 / 3014 / 20
Median age*, years (IQR)67 (64–76)68 (58–71)0.01866 (61–72)68 (58–71)0.437
Gender* (M/F), n =39 / 847 / 210.12626 / 827 / 70.770
Mean ECOG-PS* (±SD)0.0±0.20.0±0.00.1600.1±0.20.0±0.00.156
Median follow-up, months (IQR)72 (53–112)97 (70–125)0.09373 (54–98)101 (74–126)0.139
Neoadjuvant chemotherapy, n =18 (38%)35 (51%)0.18613 (38%)16 (47%)0.624
TNM classification
    cT* (±SD)2.4±0.92.3±0.80.2592.4±0.92.2±0.80.212
    pT (±SD)2.1±1.21.4±1.20.0012.0±1.21.3±1.10.009
    pN+, n =7 (15%)1 (1.5%)0.0086 (18%)1 (3%)0.105
Cardiovascular disease*, n =3 (6%)9 (13%)0.3542 (6%)1 (3%)0.555
Hypertension*, n =21 (45%)27 (40%)0.70114 (41%)14 (41%)1.000
Diabetes*, n =5 (11%)8 (12%)1.0005 (15%)6 (18%)0.742
Median blood loss, kg (IQR)1.5 (0.9–2.3)1.3 (0.9–2.0)0.1311.4 (1.1–1.9)1.3 (0.9–1.6)0.153
Median operative duration, hours (IQR)4.7 (4.0–6.3)5.0 (4.4–6.2)0.8974.8 (4.0–6.2)4.8 (4.5–6.0)0.789
Postoperative Complications, n =18 (38%)26 (38%)1.00019 (56%)19 (56%)1.000
Postoperative hydronephrosis (> G1), n =16 (34%)5 (7%)<0.00112 (35%)4 (12%)0.043
Ureteral stent, n =23 (49%)0 (0%)<0.00115 (44%)0 (0%)<0.001
    Ileal conduit, stent (+)2 (12%)1 (7%)
    Cutaneous ureterostomy, stent (+)21 (70%)14 (70%)
Recurrence, n =15 (32%)6 (9%)0.00310 (29%)2 (6%)0.023
Chemotherapy for recurrent disease, n =14 (30%)4 (6%)0.0019 (27%)1 (2.9%)<0.001
Median cycle (IQR)4 (2–6)4 (1–5)0.4136 (3–14)3 (1–4)0.029

* applied for propensity score-matching SD, standard deviation; IQC, interquartile range.

Table 3

Multivariate Cox regression analyses of risk factors for postoperative stage 3B CKD (eGFR < 45 mL/min/1.73 m2).

Incontinent urinary diversion was divided into 2 groups, and compared with orthotopic ileal neobladder in the model 2. Comorbidities included past history of CVD, HTN, or DM.

Variables (Model 1)Fisk factorsP valueHR95%CI
AgeOlder than 67 years0.0432.901.03–8.13
ComorbiditiesPre-existing0.1102.400.82–7.02
eGFR before surgery< 60 ml/min/1.73m20.0203.251.20–8.80
Stent indwellingPositive0.1630.400.11–1.45
Postoperative hydronephrosisGreater than grade 10.0025.151.81–14.6
Tumor recurrencePositive0.9000.910.22–3.71
Chemotherapy for recurrent diseasePositive0.2900.430.09–2.04
Urinary diversionIncontinent diversion0.0164.411.33–14.7
Variables (Model 2)
AgeOlder than 67 years0.0253.471.17–10.4
ComorbiditiesPre-existing0.1292.320.78–6.87
eGFR before surgery< 60 ml/min/1.73m20.0163.321.25–8.82
Stent indwellingPositive0.0650.220.04–1.10
Postoperative hydronephrosisGreater than grade 10.0034.811.70–13.7
Tumor recurrencePositive0.9690.970.23–4.11
Chemotherapy for recurrent diseasePositive0.1960.330.06–1.77
Urinary diversion (ref. neobladder)Cutaneous ureterostomy0.0128.921.63–48.7
Ileal conduit0.0693.440.91–13.1
* applied for propensity score-matching SD, standard deviation; IQC, interquartile range.

Multivariate Cox regression analyses of risk factors for postoperative stage 3B CKD (eGFR < 45 mL/min/1.73 m2).

Incontinent urinary diversion was divided into 2 groups, and compared with orthotopic ileal neobladder in the model 2. Comorbidities included past history of CVD, HTN, or DM.
  1 in total

1.  Renal Function Outcomes and Risk Factors for Stage 3B Chronic Kidney Disease after Urinary Diversion in Patients with Muscle Invasive Bladder Cancer [corrected].

Authors:  Shingo Hatakeyama; Takuya Koie; Takuma Narita; Shogo Hosogoe; Hayato Yamamoto; Yuki Tobisawa; Tohru Yoneyama; Takahiro Yoneyama; Yasuhiro Hashimoto; Chikara Ohyama
Journal:  PLoS One       Date:  2016-02-22       Impact factor: 3.240

  1 in total

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