Marcela Tamayo y Ortiz1, Martha María Téllez-Rojo2, Howard Hu3, Mauricio Hernández-Ávila4, Robert Wright5, Chitra Amarasiriwardena6, Nicola Lupoli7, Adriana Mercado-García8, Ivan Pantic9, Héctor Lamadrid-Figueroa10. 1. National Council of Science and Technology, Avenida Insurgentes Sur 1582, Benito Juárez, Crédito Constructor, 03940 Ciudad de México, D.F, Mexico; National Institute of Public Health, Universidad No. 655 Colonia Santa María, Ahuacatitlán, Cerrada Los Pinos y Caminera C.P. 62100, Cuernavaca, Morelos, Mexico. Electronic address: marcela.tamayo@insp.mx. 2. National Institute of Public Health, Universidad No. 655 Colonia Santa María, Ahuacatitlán, Cerrada Los Pinos y Caminera C.P. 62100, Cuernavaca, Morelos, Mexico. Electronic address: mmtellez@insp.mx. 3. University of Toronto, Dalla Lana School of Public Health, 6, 155 College St, Toronto, ON, Canada M5T 3M7. Electronic address: howard.hu@utoronto.ca. 4. National Institute of Public Health, Universidad No. 655 Colonia Santa María, Ahuacatitlán, Cerrada Los Pinos y Caminera C.P. 62100, Cuernavaca, Morelos, Mexico. Electronic address: mhernan@insp.mx. 5. Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY 10029, United States. Electronic address: robert.wright@mssm.edu. 6. Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY 10029, United States. Electronic address: chitra.amarasiriwardena@mssm.edu. 7. Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, MA 02115, United States. Electronic address: nicolalupoli@yahoo.com. 8. National Institute of Public Health, Universidad No. 655 Colonia Santa María, Ahuacatitlán, Cerrada Los Pinos y Caminera C.P. 62100, Cuernavaca, Morelos, Mexico. Electronic address: adrianam@insp.mx. 9. National Institute of Perinatology, Calle Montes Urales #800, Miguel Hidalgo Lomas Virreyes, 11000 Ciudad de México, D.F, Mexico. Electronic address: ivandpantic@gmail.com. 10. National Institute of Public Health, Universidad No. 655 Colonia Santa María, Ahuacatitlán, Cerrada Los Pinos y Caminera C.P. 62100, Cuernavaca, Morelos, Mexico. Electronic address: hlamadrid@insp.mx.
Abstract
BACKGROUND: Recent studies have shown that lead exposure continues to pose a health risk in Mexico. Children are a vulnerable population for lead effects and Mexican candy has been found to be a source of exposure in children. There are no previous studies that estimates lead concentrations in candy that children living in Mexico City consume and its association with their blood lead level. OBJECTIVES: To evaluate whether there is an association between reported recent consumption of candies identified to have lead, and blood lead levels among children in Mexico City. METHODS: A subsample of 171 children ages 2-6 years old, from the Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) cohort study was assessed between June 2006 and July 2007. The candy reported most frequently were analyzed for lead using ICP-MS. The total weekly intake of lead through the consumption of candy in the previous week was calculated. Capillary blood lead levels (BLL) were measured using LeadCare (anodic stripping voltammetry). RESULTS: Lead concentrations ≥0.1ppm, the FDA permitted level (range: 0.13-0.7ppm) were found in 6 samples out of 138 samples from 44 different brands of candy. Median BLL in children was 4.5µg/dl. After adjusting for child's sex, age, BMI, maternal education & occupation, milk consumption, sucking the candy wrapper, use of lead-glazed pottery, child exposure behavior, living near a lead exposure site and use of folk remedies, an increase of 1µg of lead ingested through candy per week was associated with 3% change (95% CI: 0.1%, 5.2%) in BLL. CONCLUSIONS: Although lead concentrations in candy were mostly below the FDA permitted level, high lead concentrations were detected in 4% of the candy samples and 12% of brands analyzed. Although candy intake was modestly associated with children's BLL, lead should not be found in consumer products, especially in candy that children can consume due to the well documented long-lasting effect of lead exposure.
BACKGROUND: Recent studies have shown that lead exposure continues to pose a health risk in Mexico. Children are a vulnerable population for lead effects and Mexican candy has been found to be a source of exposure in children. There are no previous studies that estimates lead concentrations in candy that children living in Mexico City consume and its association with their blood lead level. OBJECTIVES: To evaluate whether there is an association between reported recent consumption of candies identified to have lead, and blood lead levels among children in Mexico City. METHODS: A subsample of 171 children ages 2-6 years old, from the Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) cohort study was assessed between June 2006 and July 2007. The candy reported most frequently were analyzed for lead using ICP-MS. The total weekly intake of lead through the consumption of candy in the previous week was calculated. Capillary blood lead levels (BLL) were measured using LeadCare (anodic stripping voltammetry). RESULTS: Lead concentrations ≥0.1ppm, the FDA permitted level (range: 0.13-0.7ppm) were found in 6 samples out of 138 samples from 44 different brands of candy. Median BLL in children was 4.5µg/dl. After adjusting for child's sex, age, BMI, maternal education & occupation, milk consumption, sucking the candy wrapper, use of lead-glazed pottery, child exposure behavior, living near a lead exposure site and use of folk remedies, an increase of 1µg of lead ingested through candy per week was associated with 3% change (95% CI: 0.1%, 5.2%) in BLL. CONCLUSIONS: Although lead concentrations in candy were mostly below the FDA permitted level, high lead concentrations were detected in 4% of the candy samples and 12% of brands analyzed. Although candy intake was modestly associated with children's BLL, lead should not be found in consumer products, especially in candy that children can consume due to the well documented long-lasting effect of lead exposure.
Authors: Katarzyna Kordas; Rachael Burganowski; Aditi Roy; Fabiana Peregalli; Valentina Baccino; Elizabeth Barcia; Soledad Mangieri; Virginia Ocampo; Nelly Mañay; Gabriela Martínez; Marie Vahter; Elena I Queirolo Journal: Environ Int Date: 2017-11-21 Impact factor: 9.621
Authors: Isabelle Nogueira Leroux; Ana Paula Sacone da Silva Ferreira; Júlia Prestes da Rocha Silva; Flávio Ferreira Bezerra; Fábio Ferreira da Silva; Fernanda Junqueira Salles; Maciel Santos Luz; Nílson Antônio de Assunção; Maria Regina Alves Cardoso; Kelly Polido Kaneshiro Olympio Journal: Environ Sci Pollut Res Int Date: 2018-09-11 Impact factor: 4.223
Authors: Margaret A Handley; Kali Nelson; Eric Sanford; Cassidy Clarity; Sophia Emmons-Bell; Anuhandra Gorukanti; Patrick Kennelly Journal: Environ Health Perspect Date: 2017-10-26 Impact factor: 9.031
Authors: Marcela Tamayo-Ortiz; Alison P Sanders; Maria J Rosa; Robert O Wright; Chitra Amarasiriwardena; Adriana Mercado-García; Ivan Pantic; Hector Lamadrid-Figueroa; Martha María Téllez-Rojo Journal: Ann Glob Health Date: 2020-02-25 Impact factor: 2.462