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Literature DB >> 26972440

Application of metabolomics technology in the research of Chinese medicine.

Abstract

In recent years, a novel analytical technology, metabolomics is widely used in the modern research of Chinese medicine (CM). Metabolomics adopts a "top-down" strategy to reflect the function of organisms from terminal symptoms of metabolic network and understand metabolic changes of a complete system caused by interventions. As a holistic approach, metabolomics technology, including nuclear magnetic resonance, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry, favorable to express the meaning of basic theories of CM, CM syndrome and Chinese herb. Therefore, we believe that metabolomics technology will greatly benefit to development for the research of CM in the light of modern sciences.

Entities: Disease

Keywords: Chinese herb; Chinese medicine syndrome; Chinese medicine theory; metabolomics

Mesh：

Year: 2014 PMID： 26972440 DOI： 10.1007/s11655-014-1348-8

Source DB: PubMed Journal: Chin J Integr Med ISSN： 1672-0415 Impact factor: 1.978

22 in total

1. Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics.

Authors: Yan Gu; Yifei Zhang; Xianzhe Shi; Xiaoying Li; Jie Hong; Jing Chen; Weiqiong Gu; Xin Lu; Guowang Xu; Guang Ning
Journal: Talanta Date: 2010-01-18 Impact factor: 6.057

2. [NMR-spectroscopy-based metabonomic approach to analysis of Siwutang, a novel prescription, treated blood deficiency in mice].

Authors: Mu Wang; Weiqing Rang; Qi Zhang; Chao Huo; Zengchun Ma; Yuguang Wang; Xianzhong Yan; Yue Gao
Journal: Zhongguo Zhong Yao Za Zhi Date: 2010-03

3. Metabonomic study on the biochemical profiles of a hydrocortisone-induced animal model.

Authors: Minjun Chen; Liping Zhao; Wei Jia
Journal: J Proteome Res Date: 2005 Nov-Dec Impact factor: 4.466

Review 4. Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology.

Authors: Mei Wang; Robert-Jan A N Lamers; Henrie A A J Korthout; Joop H J van Nesselrooij; Renger F Witkamp; Rob van der Heijden; Peter J Voshol; Louis M Havekes; Rob Verpoorte; Jan van der Greef
Journal: Phytother Res Date: 2005-03 Impact factor: 5.878

Review 5. Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine.

Authors: Yong-Min Lao; Jian-Guo Jiang; Lu Yan
Journal: Br J Pharmacol Date: 2009-06-05 Impact factor: 8.739

6. [Systemic biologic study on traditional Chinese medicine--a short-lived fad or a long-term policy?].

Authors: Ming-mei Zhou; Wei Jia; Pei-gen Xiao
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi Date: 2008-09

Review 7. [Integration of metabonomics technology and its application in modernization of traditional Chinese medicine].

Authors: Chao Zhu; Ping Hu; Qiong-lin Liang; Yi-ming Wang; Guo-an Luo
Journal: Yao Xue Xue Bao Date: 2008-07

8. [Effects of the extracts from decoction for resuscitation and its component herbs on PGI2, TXA2 and NO release from rat vascular endothelial cells under hypoxia in vitro].

Authors: Ping Liu; Ying-chun Ge; Tian-shu Ma; Hui-jun Ren; Ya-juan Xu; Dong-ming Xu
Journal: Zhongguo Zhong Yao Za Zhi Date: 2004-10

Review 9. Metabolic systems biology.

Authors: Bernhard Palsson
Journal: FEBS Lett Date: 2009-12-17 Impact factor: 4.124

10. Metabolomic analysis of biofluids from rats treated with Aconitum alkaloids using nuclear magnetic resonance and gas chromatography/time-of-flight mass spectrometry.

Authors: Bo Sun; Ling Li; Shengming Wu; Qi Zhang; Haijing Li; Hebing Chen; Famei Li; Fangting Dong; Xianzhong Yan
Journal: Anal Biochem Date: 2009-08-14 Impact factor: 3.365

2 in total

1. Cardioprotective effects and mechanism of Radix Salviae miltiorrhizae and Lignum Dalbergiae odoriferae on rat myocardial ischemia/reperfusion injury.

Authors: Fei Mu; Jialin Duan; Haixu Bian; Ying Yin; Yanrong Zhu; Guo Wei; Yue Guan; Yanhua Wang; Chao Guo; Aidong Wen; Yong Yang; Miaomiao Xi
Journal: Mol Med Rep Date: 2017-06-20 Impact factor: 2.952

Review 2. Understanding the Functional Activity of Polyphenols Using Omics-Based Approaches.

Authors: Wenjin Si; Yangdong Zhang; Xiang Li; Yufeng Du; Qingbiao Xu
Journal: Nutrients Date: 2021-11-05 Impact factor: 5.717

2 in total