INTRODUCTION: The aim of this study was to test the clinimetric properties of the Comprehensive Cervical Dystonia Rating Scale. This is a modular scale with modifications of the Toronto Western Spasmodic Torticollis Rating Scale (composed of three subscales assessing motor severity, disability, and pain) now referred to as the revised Toronto Western Spasmodic Torticollis Scale-2; a newly developed psychiatric screening instrument; and the Cervical Dystonia Impact Profile-58 as a quality of life measure. METHODS: Ten dystonia experts rated subjects with cervical dystonia using the comprehensive scale. Clinimetric techniques assessed each module of the scale for reliability, item correlation, and factor structure. RESULTS: There were 208 cervical dystonia patients (73% women; age, 59 ± 10 years; duration, 15 ± 12 years). Internal consistency of the motor severity subscale was acceptable (Cronbach's alpha = 0.57). Item to total correlations showed that elimination of items with low correlations (<0.20) increased alpha to 0.71. Internal consistency estimates for the subscales for disability and pain were 0.88 and 0.95, respectively. The psychiatric screening scale had a Cronbach's alpha of 0.84 and satisfactory item to total correlations. When the subscales of the Toronto Western Spasmodic Torticollis Scale-2 were combined with the psychiatric screening scale, Cronbach's alpha was 0.88, and construct validity assessment demonstrated four rational factors: motor; disability; pain; and psychiatric disorders. The Cervical Dystonia Impact Profile-58 had an alpha of 0.98 and its construction was validated through a confirmatory factor analysis. CONCLUSIONS: The modules of the Comprehensive Cervical Dystonia Rating Scale are internally consistent with a logical factor structure.
INTRODUCTION: The aim of this study was to test the clinimetric properties of the Comprehensive Cervical Dystonia Rating Scale. This is a modular scale with modifications of the Toronto Western Spasmodic Torticollis Rating Scale (composed of three subscales assessing motor severity, disability, and pain) now referred to as the revised Toronto Western Spasmodic Torticollis Scale-2; a newly developed psychiatric screening instrument; and the Cervical Dystonia Impact Profile-58 as a quality of life measure. METHODS: Ten dystonia experts rated subjects with cervical dystonia using the comprehensive scale. Clinimetric techniques assessed each module of the scale for reliability, item correlation, and factor structure. RESULTS: There were 208 cervical dystoniapatients (73% women; age, 59 ± 10 years; duration, 15 ± 12 years). Internal consistency of the motor severity subscale was acceptable (Cronbach's alpha = 0.57). Item to total correlations showed that elimination of items with low correlations (<0.20) increased alpha to 0.71. Internal consistency estimates for the subscales for disability and pain were 0.88 and 0.95, respectively. The psychiatric screening scale had a Cronbach's alpha of 0.84 and satisfactory item to total correlations. When the subscales of the Toronto Western Spasmodic Torticollis Scale-2 were combined with the psychiatric screening scale, Cronbach's alpha was 0.88, and construct validity assessment demonstrated four rational factors: motor; disability; pain; and psychiatric disorders. The Cervical Dystonia Impact Profile-58 had an alpha of 0.98 and its construction was validated through a confirmatory factor analysis. CONCLUSIONS: The modules of the Comprehensive Cervical Dystonia Rating Scale are internally consistent with a logical factor structure.
Authors: Elizabeth Cisneros; Glenn T Stebbins; Qiyu Chen; Jeanne P Vu; Casey N Benadof; Zheng Zhang; Richard L Barbano; Susan H Fox; Christopher G Goetz; Joseph Jankovic; Hyder A Jinnah; Joel S Perlmutter; Charles H Adler; Stewart A Factor; Stephen G Reich; Ramon Rodriguez; Lawrence L Severt; Natividad P Stover; Brian D Berman; Cynthia L Comella; David A Peterson Journal: J Neurol Sci Date: 2020-11-01 Impact factor: 3.181
Authors: Jeanne P Vu; Ha Yeon Lee; Qiyu Chen; Elizabeth Cisneros; Richard L Barbano; Christopher G Goetz; Joseph Jankovic; Hyder A Jinnah; Joel S Perlmutter; Brian D Berman; Mark I Appelbaum; Glenn T Stebbins; Cynthia L Comella; David A Peterson Journal: J Neurol Date: 2021-01-08 Impact factor: 4.849
Authors: Jeanne P Vu; Elizabeth Cisneros; Ha Yeon Lee; Linh Le; Qiyu Chen; Xiaoyan A Guo; Ryin Rouzbehani; Joseph Jankovic; Stewart Factor; Christopher G Goetz; Richard L Barbano; Joel S Perlmutter; Hyder A Jinnah; Sarah Pirio Richardson; Glenn T Stebbins; Rodger Elble; Cynthia L Comella; David A Peterson Journal: J Neurol Sci Date: 2022-01-22 Impact factor: 4.553
Authors: Lisa Klingelhoefer; Kallol R Chaudhuri; Christoph Kamm; Pablo Martinez-Martin; Kailash Bhatia; Anna Sauerbier; Maximilian Kaiser; Carmen Rodriguez-Blazquez; Bettina Balint; Robert Untucht; Lynsey J Hall; Lauritz Mildenstein; Miriam Wienecke; Davide Martino; Olaf Gregor; Alexander Storch; Heinz Reichmann Journal: Ann Clin Transl Neurol Date: 2019-09-27 Impact factor: 4.511
Authors: Megan E Wadon; Grace A Bailey; Zehra Yilmaz; Emily Hubbard; Meshari AlSaeed; Amy Robinson; Duncan McLauchlan; Richard L Barbano; Laura Marsh; Stewart A Factor; Susan H Fox; Charles H Adler; Ramon L Rodriguez; Cynthia L Comella; Stephen G Reich; William L Severt; Christopher G Goetz; Joel S Perlmutter; Hyder A Jinnah; Katharine E Harding; Cynthia Sandor; Kathryn J Peall Journal: Brain Behav Date: 2021-07-21 Impact factor: 2.708