Literature DB >> 26970624

Zygotic Genome Activators, Developmental Timing, and Pluripotency.

Daria Onichtchouk1, Wolfgang Driever2.   

Abstract

The transcription factors Pou5f1, Sox2, and Nanog are central regulators of pluripotency in mammalian ES and iPS cells. In vertebrate embryos, Pou5f1/3, SoxB1, and Nanog control zygotic genome activation and participate in lineage decisions. We review the current knowledge of the roles of these genes in developing vertebrate embryos from fish to mammals and suggest a model for pluripotency gene regulatory network functions in early development.
© 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Blastula; Differentiation; Embryo; Embryonic stem cells; Gene regulatory network; Oct4; Pattern formation; Pluripotency; Pou5f3; Zygotic genome activation

Mesh:

Substances:

Year:  2016        PMID: 26970624     DOI: 10.1016/bs.ctdb.2015.12.004

Source DB:  PubMed          Journal:  Curr Top Dev Biol        ISSN: 0070-2153            Impact factor:   4.897


  9 in total

Review 1.  Mechanisms regulating zygotic genome activation.

Authors:  Katharine N Schulz; Melissa M Harrison
Journal:  Nat Rev Genet       Date:  2019-04       Impact factor: 53.242

2.  The primary role of zebrafish nanog is in extra-embryonic tissue.

Authors:  James A Gagnon; Kamal Obbad; Alexander F Schier
Journal:  Development       Date:  2018-01-09       Impact factor: 6.868

3.  Zygotic Genome Activation: Critical Prelude to the Most Important Time of Your Life.

Authors:  Vladimir Korzh
Journal:  Methods Mol Biol       Date:  2021

4.  Silencing XIST on the future active X: Searching human and bovine preimplantation embryos for the repressor.

Authors:  Melis A Aksit; Bo Yu; Bernard A J Roelen; Barbara R Migeon
Journal:  Eur J Hum Genet       Date:  2022-05-19       Impact factor: 4.246

Review 5.  The functional diversity of the POUV-class proteins across vertebrates.

Authors:  Evgeny I Bakhmet; Alexey N Tomilin
Journal:  Open Biol       Date:  2022-06-29       Impact factor: 7.124

6.  CTCF looping is established during gastrulation in medaka embryos.

Authors:  Ryohei Nakamura; Yuichi Motai; Masahiko Kumagai; Candice L Wike; Haruyo Nishiyama; Yoichiro Nakatani; Neva C Durand; Kaori Kondo; Takashi Kondo; Tatsuya Tsukahara; Atsuko Shimada; Bradley R Cairns; Erez Lieberman Aiden; Shinichi Morishita; Hiroyuki Takeda
Journal:  Genome Res       Date:  2021-05-18       Impact factor: 9.043

Review 7.  Key features of the POU transcription factor Oct4 from an evolutionary perspective.

Authors:  Evgeny I Bakhmet; Alexey N Tomilin
Journal:  Cell Mol Life Sci       Date:  2021-10-26       Impact factor: 9.261

8.  Expression Profiling of Differentiating Emerin-Null Myogenic Progenitor Identifies Molecular Pathways Implicated in Their Impaired Differentiation.

Authors:  Ashvin Iyer; Adam J Koch; James M Holaska
Journal:  Cells       Date:  2017-10-22       Impact factor: 6.600

9.  Dynamics of DNA methylomes underlie oyster development.

Authors:  Guillaume Riviere; Yan He; Samuele Tecchio; Elizabeth Crowell; Michaël Gras; Pascal Sourdaine; Ximing Guo; Pascal Favrel
Journal:  PLoS Genet       Date:  2017-06-08       Impact factor: 5.917

  9 in total

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