Literature DB >> 26970620

Cancer in Drosophila: Imaginal Discs as a Model for Epithelial Tumor Formation.

Héctor Herranz1, Teresa Eichenlaub1, Stephen M Cohen2.   

Abstract

Cancer genomics has greatly increased our understanding of the complexity of the genetic and epigenetic changes found in human tumors. Understanding the functional relationships among these elements calls for the use of flexible genetic models. We discuss the use of Drosophila models to study cooperation among genetic factors that contribute to disease progression.
© 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cancer; Disease model; Drosophila; EGFR; Epithelial–mesenchymal transition; Imaginal disc; Metastasis

Mesh：

Year:  2016        PMID： 26970620     DOI： 10.1016/bs.ctdb.2015.11.037

Source DB:  PubMed          Journal:  Curr Top Dev Biol        ISSN： 0070-2153            Impact factor:   4.897


  21 in total

1.  dTcf/Pangolin suppresses growth and tumor formation in Drosophila.

Authors:  Shilin Song; Diana Andrejeva; Flávia C P Freitas; Stephen M Cohen; Héctor Herranz
Journal:  Proc Natl Acad Sci U S A       Date:  2019-06-24       Impact factor: 11.205

2.  Tissue-autonomous immune response regulates stress signaling during hypertrophy.

Authors:  Robert Krautz; Dilan Khalili; Ulrich Theopold
Journal:  Elife       Date:  2020-12-30       Impact factor: 8.140

3.  Studying Mitochondrial Structure and Function in Drosophila Ovaries.

Authors:  Danitra J Parker; Aida Moran; Kasturi Mitra
Journal:  J Vis Exp       Date:  2017-01-04       Impact factor: 1.355

4.  EGFRAP encodes a new negative regulator of the EGFR acting in both normal and oncogenic EGFR/Ras-driven tissue morphogenesis.

Authors:  Jennifer Soler Beatty; Cristina Molnar; Carlos M Luque; Jose F de Celis; María D Martín-Bermudo
Journal:  PLoS Genet       Date:  2021-08-19       Impact factor: 5.917

Review 5.  Non-mammalian models of multiple endocrine neoplasia type 2.

Authors:  Tirtha K Das; Ross L Cagan
Journal:  Endocr Relat Cancer       Date:  2018-02       Impact factor: 5.678

6.  Signalling crosstalk during early tumorigenesis in the absence of Polycomb silencing.

Authors:  Jorge V Beira; Joana Torres; Renato Paro
Journal:  PLoS Genet       Date:  2018-01-22       Impact factor: 5.917

7.  The chromatin remodeling BAP complex limits tumor-promoting activity of the Hippo pathway effector Yki to prevent neoplastic transformation in Drosophila epithelia.

Authors:  Shilin Song; Héctor Herranz; Stephen M Cohen
Journal:  Dis Model Mech       Date:  2017-07-28       Impact factor: 5.758

8.  Homeodomain-interacting protein kinase promotes tumorigenesis and metastatic cell behavior.

Authors:  Jessica A Blaquiere; Kenneth Kin Lam Wong; Stephen D Kinsey; Jin Wu; Esther M Verheyen
Journal:  Dis Model Mech       Date:  2018-01-17       Impact factor: 5.758

Review 9.  Modelling Cooperative Tumorigenesis in Drosophila.

Authors:  Helena E Richardson; Marta Portela
Journal:  Biomed Res Int       Date:  2018-03-06       Impact factor: 3.411

Review 10.  Metabolic reprogramming in cancer: mechanistic insights from Drosophila.

Authors:  Kenneth Kin Lam Wong; Esther M Verheyen
Journal:  Dis Model Mech       Date:  2021-07-09       Impact factor: 5.758
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