| Literature DB >> 26970136 |
Priscila H Goncalves1, Jairo M Montezuma-Rusca2, Robert Yarchoan1, Thomas S Uldrick3.
Abstract
People living with human immunodeficiency virus (HIV) are living longer since the advent of effective combined antiretroviral therapy (cART). While cART substantially decreases the risk of developing some cancers, HIV-infected individuals remain at high risk for Kaposi sarcoma, lymphoma, and several solid tumors. Currently HIV-infected patients represent an aging group, and malignancies have become a leading cause of morbidity and mortality. Tailored cancer-prevention strategies are needed for this population. In this review we describe the etiologic agents and pathogenesis of common malignancies in the setting of HIV, as well as current evidence for cancer prevention strategies and screening programs. Published by Elsevier Inc.Entities:
Keywords: AIDS-related lymphoma; HIV; HPV vaccines; Kaposi sarcoma; Neoplasms
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Year: 2015 PMID: 26970136 PMCID: PMC4789150 DOI: 10.1053/j.seminoncol.2015.09.011
Source DB: PubMed Journal: Semin Oncol ISSN: 0093-7754 Impact factor: 4.929