| Literature DB >> 26970125 |
Asad Umar1, Vernon E Steele2, David G Menter3, Ernest T Hawk3.
Abstract
Various clinical and epidemiologic studies show that nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin and cyclooxygenase inhibitors (COXIBs) help prevent cancer. Since eicosanoid metabolism is the main inhibitory targets of these drugs the resulting molecular and biological impact is generally accepted. As our knowledge base and technology progress we are learning that additional targets may be involved. This review attempts to summarize these new developments in the field. Published by Elsevier Inc.Entities:
Keywords: Aspirin; Cancer prevention; Inflammation; Non-steroidal anti-inflammatory drugs (NSAID)
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Year: 2015 PMID: 26970125 DOI: 10.1053/j.seminoncol.2015.09.010
Source DB: PubMed Journal: Semin Oncol ISSN: 0093-7754 Impact factor: 4.929