Literature DB >> 26970077

Mixed vitiligo of Blaschko lines: a newly discovered presentation of vitiligo responsive to combination treatment.

Maja Kovacevic1,2, Andrija Stanimirovic1,3, Majda Vucic4, Andy Goren2,5, Mirna Situm6, Vesna Lukinovic Skudar7, Torello Lotti2.   

Abstract

Vitiligo, depigmenting disorder of the skin and mucous membranes, affects up to 1% of the population worldwide. It is classified into four major types: segmental, non-segmental, mixed, and unclassified type. Non-segmental vitiligo refers to non-dermatomal distribution of lesions, while dermatomal distribution of lesions is present in patients with segmental vitiligo. Segmental vitiligo can also follow Blaschko lines - pathways of epidermal cell migration and proliferation during the development of the fetus. Here, we present patient with segmental and non-segmental vitiligo following Blaschko lines with excellent therapeutic response to combined therapy. Prior to our report, a case of segmental and non-segmental vitiligo followed by Blaschko lines was never described, therefore we suggest the term "mixed vitiligo of Blaschko lines" to describe this entity. This is also a rare case in which 90% repigmentation was achieved in patient with segmental and nonsegmental vitiligo following Blaschko lines in only 2 months of combined therapy.
© 2016 Wiley Periodicals, Inc.

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Keywords:  Blaschko lines; mixed vitiligo; vitiligo

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Year:  2016        PMID: 26970077     DOI: 10.1111/dth.12345

Source DB:  PubMed          Journal:  Dermatol Ther        ISSN: 1396-0296            Impact factor:   2.851


  1 in total

1.  Linear and Whorled Nevoid Hypermelanosis with Depigmentation.

Authors:  Preema Sinha; Manas Chatterjee; Kamlesh K Singh; Aradhana Sood
Journal:  Indian Dermatol Online J       Date:  2017 Mar-Apr
  1 in total

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