Literature DB >> 26969972

Applied Developmental Biology: Making Human Pancreatic Beta Cells for Diabetics.

Douglas A Melton1.   

Abstract

Understanding the genes and signaling pathways that determine the differentiation and fate of a cell is a central goal of developmental biology. Using that information to gain mastery over the fates of cells presents new approaches to cell transplantation and drug discovery for human diseases including diabetes.
© 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Beta cell; Diabetes; Differentiation; Pancreas; Stem cell

Mesh：

Year:  2016        PMID： 26969972     DOI： 10.1016/bs.ctdb.2015.11.013

Source DB:  PubMed          Journal:  Curr Top Dev Biol        ISSN： 0070-2153            Impact factor:   4.897


  6 in total

1.  Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.

Authors:  Roberta Azzarelli; Christopher Hurley; Magdalena K Sznurkowska; Steffen Rulands; Laura Hardwick; Ivonne Gamper; Fahad Ali; Laura McCracken; Christopher Hindley; Fiona McDuff; Sonia Nestorowa; Richard Kemp; Kenneth Jones; Berthold Göttgens; Meritxell Huch; Gerard Evan; Benjamin D Simons; Douglas Winton; Anna Philpott
Journal:  Dev Cell       Date:  2017-04-27       Impact factor: 12.270

2.  A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and in vivo tracking of therapeutic cells.

Authors:  Martha Lopez-Yrigoyen; Antonella Fidanza; Luca Cassetta; Richard A Axton; A Helen Taylor; Jose Meseguer-Ripolles; Anestis Tsakiridis; Valerie Wilson; David C Hay; Jeffrey W Pollard; Lesley M Forrester
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2018-07-05       Impact factor: 6.237

3.  Induction of functional islet-like cells from human iPS cells by suspension culture.

Authors:  Shigeharu G Yabe; Satsuki Fukuda; Junko Nishida; Fujie Takeda; Kiyoko Nashiro; Hitoshi Okochi
Journal:  Regen Ther       Date:  2019-01-02       Impact factor: 3.419

4.  In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism.

Authors:  Thomas Aga Legøy; Andreas F Mathisen; Zaidon Salim; Heidrun Vethe; Yngvild Bjørlykke; Shadab Abadpour; Joao A Paulo; Hanne Scholz; Helge Ræder; Luiza Ghila; Simona Chera
Journal:  Front Cell Dev Biol       Date:  2020-02-25

5.  Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells.

Authors:  Roberta Azzarelli; Steffen Rulands; Sonia Nestorowa; John Davies; Sara Campinoti; Sébastien Gillotin; Paola Bonfanti; Berthold Göttgens; Meritxell Huch; Benjamin Simons; Anna Philpott
Journal:  Sci Rep       Date:  2018-10-18       Impact factor: 4.379

6.  Tracing the cellular basis of islet specification in mouse pancreas.

Authors:  Magdalena K Sznurkowska; Edouard Hannezo; Roberta Azzarelli; Lemonia Chatzeli; Tatsuro Ikeda; Shosei Yoshida; Anna Philpott; Benjamin D Simons
Journal:  Nat Commun       Date:  2020-10-07       Impact factor: 14.919
  6 in total

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