Literature DB >> 26969242

Diabetes Mellitus Type 2: A Driving Force for Urological Complications.

Rashid K Sayyid1, Neil E Fleshner2.   

Abstract

Type 2 diabetes mellitus (T2DM) is a growing epidemic associated with many adverse complications. Urological complications of diabetes mellitus in men are gaining recognition. Previously unknown associations between T2DM and risk for prostate cancer, bladder cancer, renal cell carcinomas, urinary tract infections, nephrolithiasis, penile lesions, androgen deficiency, and erectile dysfunction have been discovered. Significantly, metformin could play a role in the management of urological malignancies, and therapies used for management of these cancers could in return lead to increased risk for diabetes. In this review, we aim to bridge the gap between T2DM and urological complications by discussing the latest findings in these fields, with the ultimate goal being improved patient care on both fronts. Crown
Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  bladder; kidney; metformin; prostate; testosterone; type 2 diabetes mellitus

Mesh:

Substances:

Year:  2016        PMID: 26969242     DOI: 10.1016/j.tem.2016.02.006

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN: 1043-2760            Impact factor:   12.015


  6 in total

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Review 2.  Path of translational discovery of urological complications of obesity and diabetes.

Authors:  Firouz Daneshgari; Guiming Liu; Ann T Hanna-Mitchell
Journal:  Am J Physiol Renal Physiol       Date:  2017-01-04

3.  Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6.

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Authors:  Sandra Constantin; Florentina Geanina Lupascu; Maria Apotrosoaei; Ioana Mirela Vasincu; Dan Lupascu; Frederic Buron; Sylvain Routier; Lenuta Profire
Journal:  Chem Cent J       Date:  2017-02-01       Impact factor: 4.215

5.  A Systematic Study of Dysregulated MicroRNA in Type 2 Diabetes Mellitus.

Authors:  Yuqing He; Yuanlin Ding; Biyu Liang; Juanjuan Lin; Taek-Kyun Kim; Haibing Yu; Hanwei Hang; Kai Wang
Journal:  Int J Mol Sci       Date:  2017-02-28       Impact factor: 5.923

6.  miR-363 Alleviates Detrusor Fibrosis via the TGF-β1/Smad Signaling Pathway by Targeting Col1a2 in Rat Models of STZ-Induced T2DM.

Authors:  Xue-Feng Li; Shu-Hua Zhang; Gui-Feng Liu; Shao-Nan Yu
Journal:  Mol Ther Nucleic Acids       Date:  2020-07-10       Impact factor: 10.183

  6 in total

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