Timothy J Bernard1, Neil R Friedman2, Nicholas V Stence3, William Jones4, Rebecca Ichord5, Catherine Amlie-Lefond6, Michael M Dowling7, Michael J Rivkin8. 1. Hemophilia and Thrombosis Center, University of Colorado School of Medicine, Aurora, Colorado; Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado. Electronic address: Timothy.Bernard@childrenscolorado.org. 2. Center for Pediatric Neurology, Neurological Institute, Cleveland Clinic, Cleveland, Ohio. 3. Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado; Department of Radiology, University of Colorado School of Medicine, Aurora, Colorado. 4. Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado. 5. Department of Neurology, Children's Hospital of Philadelphia, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania. 6. Seattle Children's Hospital, Department of Neurology, University of Washington, Seattle, Washington. 7. Division of Pediatric Neurology, Department of Pediatrics and Neurology, University of Texas Southwestern Medical Center Dallas, Dallas, Texas. 8. Department of Neurology, Boston Children's Hospital, Boston, Massachusetts; Department of Psychiatry, Boston Children's Hospital, Boston, Massachusetts; Department of Radiology, Boston Children's Hospital, Boston, Massachusetts; Department of Neurology, Harvard Medical School, Boston, Massachusetts.
Abstract
BACKGROUND: Childhood arterial ischemic stroke is an important cause of morbidity and mortality in children. Hyperacute treatment strategies remain controversial and challenging, especially in the setting of increasingly proven medical and endovascular options in adults. Although national and international pediatric guidelines have given initial direction about acute therapy and management, pediatric centers have traditionally lacked the infrastructure to triage, diagnose, and treat childhood arterial ischemic stroke quickly. METHODS: In the past 10 years, researchers in the International Pediatric Stroke Study and Thrombolysis in Pediatric Stroke study have initiated early strategies for establishing pediatric specific stroke alerts. RESULTS: We review the rationale, process and components necessary for establishing a pediatric stroke alert. CONCLUSION: Development of pediatric stroke protocols and pathways, with evidence-based acute management strategies and supportive care where possible, facilitates the evaluation, management, and treatment of an acute pediatric stroke.
BACKGROUND: Childhood arterial ischemic stroke is an important cause of morbidity and mortality in children. Hyperacute treatment strategies remain controversial and challenging, especially in the setting of increasingly proven medical and endovascular options in adults. Although national and international pediatric guidelines have given initial direction about acute therapy and management, pediatric centers have traditionally lacked the infrastructure to triage, diagnose, and treat childhood arterial ischemic stroke quickly. METHODS: In the past 10 years, researchers in the International Pediatric Stroke Study and Thrombolysis in Pediatric Stroke study have initiated early strategies for establishing pediatric specific stroke alerts. RESULTS: We review the rationale, process and components necessary for establishing a pediatric stroke alert. CONCLUSION: Development of pediatric stroke protocols and pathways, with evidence-based acute management strategies and supportive care where possible, facilitates the evaluation, management, and treatment of an acute pediatric stroke.
Authors: David C Lauzier; Maria M Galardi; Kristin P Guilliams; Manu S Goyal; Catherine Amlie-Lefond; Danial K Hallam; Akash P Kansagra Journal: Stroke Date: 2021-03-11 Impact factor: 7.914
Authors: Michaela V Bonfert; Katharina Badura; Julia Gerstl; Ingo Borggraefe; Florian Heinen; Sebastian Schroeder; Martin Olivieri; Raphael Weinberger; Mirjam N Landgraf; Katharina Vill; Moritz Tacke; Steffen Berweck; Karl Reiter; Florian Hoffmann; Thomas Nicolai; Lucia Gerstl Journal: Front Pediatr Date: 2018-06-25 Impact factor: 3.418