Diogo Moura1, Joel Oliveira2, Eduardo G H De Moura2, Wanderlei Bernardo2, Manuel Galvão Neto3, Josemberg Campos4, Violeta B Popov5, Cristopher Thompson6. 1. Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brasil. Electronic address: dthmoura@hotmail.com. 2. Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brasil. 3. Obeso Center, São Paulo, Brasil. 4. Universidade Federal do Pernambuco, Recife, Brasil. 5. New York University School of Medicine, New York, New York. 6. Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Abstract
BACKGROUND: Obesity has become a worldwide epidemic, and many methods are currently used to reduce obesity. This systematic review shows the effectiveness of the intragastric balloon (IGB) method compared to the sham/diet (s/d) method. OBJECTIVE: To demonstrate the effectiveness of the IGB method compared to the s/d method. SETTING: Hospital das Clinicas da Universidade de São Paulo, Brazil, Public Hospital. METHODS: After searching MEDLINE, Embase, Cochrane, Lilacs, Scopus, and CINAHL, only enrolled randomized control trials comparing IGB/diet with s/d were analyzed. For qualitative analysis, 12 studies were selected, and 9 of these were acceptable for quantitative analysis. RESULTS: The IGB/diet is more effective than s/d when comparing body mass index (BMI) loss with a mean difference of 1.1 kg/m(2) by the Student's t test and 1.41 kg/m(2) by the meta-analysis, with significant differences in both. It is also more effective in weight loss (WL), with a mean difference of 2 kg by the Student's t test and 3.55 kg by the meta-analysis. In the qualitative analysis of % excess WL (%EWL), the mean %EWL is 14.0% in favor of the IGB group compared to the s/d group by the Student's t test; however, no significant difference was found between these groups by quantitative analysis. CONCLUSION: Based on randomized control trial data alone, IGB>400 mL is more effective than sham/diet in achieving BMI loss, WL, and %EWL.
BACKGROUND:Obesity has become a worldwide epidemic, and many methods are currently used to reduce obesity. This systematic review shows the effectiveness of the intragastric balloon (IGB) method compared to the sham/diet (s/d) method. OBJECTIVE: To demonstrate the effectiveness of the IGB method compared to the s/d method. SETTING: Hospital das Clinicas da Universidade de São Paulo, Brazil, Public Hospital. METHODS: After searching MEDLINE, Embase, Cochrane, Lilacs, Scopus, and CINAHL, only enrolled randomized control trials comparing IGB/diet with s/d were analyzed. For qualitative analysis, 12 studies were selected, and 9 of these were acceptable for quantitative analysis. RESULTS: The IGB/diet is more effective than s/d when comparing body mass index (BMI) loss with a mean difference of 1.1 kg/m(2) by the Student's t test and 1.41 kg/m(2) by the meta-analysis, with significant differences in both. It is also more effective in weight loss (WL), with a mean difference of 2 kg by the Student's t test and 3.55 kg by the meta-analysis. In the qualitative analysis of % excess WL (%EWL), the mean %EWL is 14.0% in favor of the IGB group compared to the s/d group by the Student's t test; however, no significant difference was found between these groups by quantitative analysis. CONCLUSION: Based on randomized control trial data alone, IGB>400 mL is more effective than sham/diet in achieving BMI loss, WL, and %EWL.
Authors: Antonio Afonso de Miranda Neto; Diogo Turiani Hourneaux de Moura; Igor Braga Ribeiro; Ahmad Khan; Shailendra Singh; Alberto Machado da Ponte Neto; Antonio Coutinho Madruga Neto; Epifanio Silvino do Monte Junior; Francisco Tustumi; Wanderley Marques Bernardo; Eduardo Guimarães Hourneaux de Moura Journal: Obes Surg Date: 2020-05 Impact factor: 4.129
Authors: Shailendra Singh; Diogo Turiani Hourneaux de Moura; Ahmad Khan; Mohammad Bilal; Michele B Ryan; Christopher C Thompson Journal: Surg Obes Relat Dis Date: 2019-12-10 Impact factor: 4.734