| Literature DB >> 26967892 |
Xiao-Hui Li1,2, Yu Zhang1, Jia-Hui Zhang1, Xiao-Nian Li1, Ming-Ming Cao1, Ying-Tong Di1, Zong-Gen Peng3, Jian-Dong Jiang3, Xiao-Jiang Hao1.
Abstract
Myritonines A-C (1-3), three new alkaloids bearing an unprecedented heterohexacyclic skeleton, were isolated from Myrioneuron tonkinensis. Their structures were determined by a combination of spectroscopic data and single-crystal X-ray diffraction analysis. Compound 3 represents the first Myrioneuron alkaloid featuring a unique trans-decahydroquinoline motif and was also found to possess a rare cyano functionality. Compounds 1 and 2 showed inhibition against the hepatitis C virus in vitro.Entities:
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Year: 2016 PMID： 26967892 DOI： 10.1021/acs.jnatprod.5b01130
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050