| Literature DB >> 26965921 |
Abstract
In this issue of Blood, Chen et al demonstrate that platelets expressing factor VIII (FVIII) shield FVIII from immune detection. In the naive FVIII null hemophilia A (HA) mouse, platelet-derived VIII prevents both a primary and memory anti-FVIII immune response, and together with total body irradiation, suppresses anti-FVIII immune response.Entities:
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Year: 2016 PMID： 26965921 DOI： 10.1182/blood-2016-01-689869
Source DB: PubMed Journal: Blood ISSN： 0006-4971 Impact factor: 22.113