J P Jeon1, Y D Cho2, J K Rhim3, D H Yoo3, W-S Cho4, H-S Kang4, J E Kim4, M H Han3. 1. From the Department of Neurosurgery (J.P.J.), Hallym University College of Medicine, Chuncheon, Korea. 2. Departments of Radiology (Y.D.C., J.K.R., D.H.Y., M.H.H.) aronnn@empal.com. 3. Departments of Radiology (Y.D.C., J.K.R., D.H.Y., M.H.H.). 4. Neurosurgery (W.s.C., H.-S.K., J.E.K.), Seoul National University College of Medicine, Seoul, Korea.
Abstract
BACKGROUND AND PURPOSE: Minor recanalization in coiled aneurysms may remain stable with time or may progress to major recanalization. Our aim was to monitor the aneurysms displaying minor recanalization in imaging studies at 6 months, gauging major recanalization rates and related risk factors through extended follow-up. MATERIALS AND METHODS: Sixty-five aneurysms (in 65 patients) showing minor recanalization in follow-up imaging at 6 months were reviewed retrospectively. Medical records and radiologic data accruing during extended monitoring (mean, 24.8 ± 8.2 months) were assessed. Univariate and multivariate analyses were conducted to identify risk factors for progression from minor-to-major recanalization. RESULTS: Progression to major recanalization was observed in 24 (36.9%) of the initially qualifying aneurysms during a follow-up of 112.5 aneurysm-years, for an annual rate of 17.84% per aneurysm-year. Progression was determined chronologically as follows: 14 (58.3%) at 6 months, 8 (33.3%) at 18 months, and 2 (8.4%) at 30 months. Stent deployment significantly decreased the occurrence of major recanalization (OR = 0.22, P = .03), whereas antiplatelet therapy (OR = 0.82, P = .75), posterior location (OR = 0.24, P = .20), and second coiling for recanalized aneurysms (OR = 0.96, P = .96) were unrelated. CONCLUSIONS: Our analysis determined a 36.9% rate of major recanalization during a follow-up of 112.5 aneurysm-years in coiled aneurysms showing minor recanalization at 6 months. Stent deployment alone conferred a protective effect, preventing further recanalization without additional treatment. Given the fair probability of late major recanalization, aneurysms showing minor recanalization at 6 months should be monitored diligently, particularly in the absence of stent placement.
BACKGROUND AND PURPOSE: Minor recanalization in coiled aneurysms may remain stable with time or may progress to major recanalization. Our aim was to monitor the aneurysms displaying minor recanalization in imaging studies at 6 months, gauging major recanalization rates and related risk factors through extended follow-up. MATERIALS AND METHODS: Sixty-five aneurysms (in 65 patients) showing minor recanalization in follow-up imaging at 6 months were reviewed retrospectively. Medical records and radiologic data accruing during extended monitoring (mean, 24.8 ± 8.2 months) were assessed. Univariate and multivariate analyses were conducted to identify risk factors for progression from minor-to-major recanalization. RESULTS: Progression to major recanalization was observed in 24 (36.9%) of the initially qualifying aneurysms during a follow-up of 112.5 aneurysm-years, for an annual rate of 17.84% per aneurysm-year. Progression was determined chronologically as follows: 14 (58.3%) at 6 months, 8 (33.3%) at 18 months, and 2 (8.4%) at 30 months. Stent deployment significantly decreased the occurrence of major recanalization (OR = 0.22, P = .03), whereas antiplatelet therapy (OR = 0.82, P = .75), posterior location (OR = 0.24, P = .20), and second coiling for recanalized aneurysms (OR = 0.96, P = .96) were unrelated. CONCLUSIONS: Our analysis determined a 36.9% rate of major recanalization during a follow-up of 112.5 aneurysm-years in coiled aneurysms showing minor recanalization at 6 months. Stent deployment alone conferred a protective effect, preventing further recanalization without additional treatment. Given the fair probability of late major recanalization, aneurysms showing minor recanalization at 6 months should be monitored diligently, particularly in the absence of stent placement.
Authors: Christopher S Ogilvy; Michelle H Chua; Matthew R Fusco; Christoph J Griessenauer; Mark R Harrigan; Ashish Sonig; Adnan H Siddiqui; Elad I Levy; Kenneth Snyder; Michael Avery; Alim Mitha; Jorma Shores; Brian L Hoh; Ajith J Thomas Journal: Neurosurgery Date: 2015-08 Impact factor: 4.654
Authors: Young Dae Cho; Jong Young Lee; Jung Hwa Seo; Seung Jin Lee; Hyun-Seung Kang; Jeong Eun Kim; Young Je Son; Keun-Hwa Jung; O-Ki Kwon; Moon Hee Han Journal: Neurosurgery Date: 2012-12 Impact factor: 4.654
Authors: Y Funakoshi; H Imamura; S Tani; H Adachi; R Fukumitsu; T Sunohara; Y Omura; Y Matsui; N Sasaki; T Fukuda; R Akiyama; K Horiuchi; S Kajiura; M Shigeyasu; K Iihara; N Sakai Journal: AJNR Am J Neuroradiol Date: 2020-05-07 Impact factor: 3.825
Authors: F Diana; A Pesce; G Toccaceli; V Muralidharan; E Raz; M Miscusi; A Raco; P Missori; S Peschillo Journal: Neurosurg Rev Date: 2021-10-07 Impact factor: 3.042
Authors: Aglaé Velasco González; P Stracke; H Nordmeyer; M Heddier; S Saleme; C Sauerland; S Berkemeyer; B Buerke; W Heindel; R Chapot Journal: Neuroradiology Date: 2018-09-05 Impact factor: 2.804